Associations among serum pro- and anti-inflammatory cytokines, metabolic mediators, body condition, and uterine disease in postpartum dairy cows

Table 4 ‘ P ’ values* from repeated measures of ANOVA for the effects of persistent uterine inflammatory condition‡, body condition score categories [low (2 and 2.5) and high (3, 3.5 and 4)] and weeks postpartum on adipokines in postpartum dairy cows

Adipokine	Effect	DF	F Value	P > F
Adiponectin	Persistent uterine inflammatory conditions	1	11.01	<0.001
	Body condition score categories	1	7.71	0.001
	Weeks in postpartum	8	13.27	0.01
Leptin	Persistent uterine inflammatory conditions	1	16.04	0.01
	Body condition score categories	1	8.65	0.01
	Weeks in postpartum	8	13.51	0.03
TNF-α	Persistent uterine inflammatory conditions	1	14.56	0.001
	Body condition score categories	1	8.44	0.009
	Weeks in postpartum	8	15.78	0.04
IL-1β	Persistent uterine inflammatory conditions	1	13.15	<0.001
	Body condition score categories	1	6.16	0.001
	Weeks in postpartum	8	16.73	0.02
IL-6	Persistent uterine inflammatory conditions	1	13.28	<0.001
	Body condition score categories	1	7.47	0.01
	Weeks in postpartum	8	13.11	0.01
Insulin	Persistent uterine inflammatory conditions	1	11.91	<0.01
	Body condition score categories	1	7.78	0.03
	Weeks in postpartum	8	16.48	0.02
IGF-1	Persistent uterine inflammatory conditions	1	16.18	<0.01
	Body condition score categories	1	8.49	0.01
	Weeks in postpartum	8	13.81	0.01

*Accounted for persistent uterine inflammatory condition by body condition score categories, persistent uterine inflammatory conditions by weeks in postpartum and body condition score categories by weeks in postpartum interactions, except for IGF-1 (P < 0.01); ‡A cow diagnosed with uterine disease at both initial and follow-up examinations was considered to have persistent inflammation.

ISSN: 1477-7827