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Table 2 Presence of ovarian OSC and emergence of oogenesis in culture

From: Immunoregulation of follicular renewal, selection, POF, and menopause in vivo, vs. neo-oogenesis in vitro, POF and ovarian infertility treatment, and a clinical trial

Case #1 Age2 POF Diagnosis CK+ OSC/ epithelial crypts Oogenesis in primary and secondary cultures Morulae
   pre/post menopause   left ov right ov primary secondary  
1 30 POF POF yes yes yes N.A. no
2 36 pre PFD4 no yes yes yes no
3 38 POF POF no no no N.A. no
4 39 pre endometriosis yes yes yes N.A. no
5 40 POF POF yes yes yes N.A. no
6 42 pre fibroids yes no yes yes yes
7 43A pre menorrhagia yes yes yes yes no
8 43B pre fibroids yes no yes yes no
9 45 pre endometriosis yes yes yes yes yes
10 48A pre menorrhagia no yes yes yes yes
11 48A pre fibroids no yes yes yes no
12 49 3 pre PFD no no no N.A. no
13 50 3 pre fibroids no no no N.A. no
14 52 3 post ovarian cyst no no no N.A. no
15 53 post PFD no yes yes yes no
16 55 post uterine bleeding yes no yes yes yes
17 60 post PFD no yes yes yes yes
18 67A post PFD yes yes yes N.A. no
19 67B post PFD yes no yes N.A. no
  1. Evaluation of menopausal status, OSC in ovaries, and presence of oogenesis and morulae in primary and secondary ovarian cultures. Data adapted from [178] and [94] with permission, © Informa UK Ltd.
  2. 1 Age arrangement.
  3. 2 Letters are added in patients exhibiting identical age.
  4. 3 Perimenopausal women.
  5. 4 Pelvic floor disorders (uterine/vaginal prolapse with or without urinary incontinence).
  6. POF, premature ovarian failure; pre, premenopause; post, postmenopause; N.A., not available.
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Reproductive Biology and Endocrinology

ISSN: 1477-7827

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