Figure 18

Intravascular degenerating human oocytes. Degenerating oocytes in venules of ovarian medulla (A D and F) and uterine endocervical stroma (E) expressing zona pellucida proteins identified by MAb clones against ZP3, ZP4 and ZP 2 [198] as indicated in panels. MAb to ZP1 was kindly provided by Dr. Satish K Gupta. Arrowheads indicate unstained oocyte nuclei, arrow in F shows an arteriole, arrow in G shows ZP expression at the oocyte surface in a normal secondary follicle. F28-F38 indicate patients’ ages. Panels A and C adapted from [139] with permission, © Elsevier.