Figure 11
Follicular selection. Selection of secondary (A-D) and preovulatory (dominant) follicles (E-G), and large antral follicle atresia (H-J) in the adult human ovary. Staining for Thy-1, HLA-DR (DR), MHC class I light chain (beta 2m) and CD68 of mature MDC, as indicated in panels. Dashed line in A indicates an "ovary-in-ovary" area exhibiting diminution of Thy-1 expression by stromal cells. B) detail from A. C and D are semi-parallel sections to B. Dashed line in E-J, follicular basement membrane. rf, resting follicles; gf, growing follicle; p, pericytes; e, endothelial cells; v, microvasculature in theca interna (t); vl, vascular layer adjacent to the follicular basement membrane; g, granulosa layer. Reprinted from [134] with permission, © Wiley-Liss.