Skip to main content

Table 6 Selected genes expression of which bear predictable leads to ovarian endometriosis among Indian women

From: Genome-wide expressions in autologous eutopic and ectopic endometrium of fertile women with endometriosis

Expression characteristics

Gene symbol (GenBank ID) [Gene name]

Fold changea

Microarrayb

RT-PCRc

Up-regulated in eutopic tissue

  

General

  

3HMGN2 (NM_005517)

4.8+1.0

2.4++0.3

[High-mobility group nucleosomal binding domain 2]

  

MKI67 (NM_002417 )

3.4+0.9

4.6+1.8

[Ki-67-like antigen]

  

NRCAM (NM_001037132)

4.5+1.6

2.1+0.5

[Neuronal cell adhesion molecule]*

  

PARG (NM_003631)

3.8+2.1

3.4+1.5

[Poly (adp-ribose) glycohydrolase]

  

TMPO (NM_001032283)

3.1+1.9

2.8+1.1

[Thymopoietin]

  

Stage 3

ATP2A2 (NM_001681)

5.1+1.9

8.6+3.5

[ATPase, Ca++ transporting, cardiac muscle,slow twitch 2]

  

CHIA (NM_021797)

3.4+1.3

7.3+1.5

[Chitinase, acidic]

  

DAPK2 (NM_014326)

6.2+2.3

9.7+1.8

[Death-associated protein kinase 2]*

  

ERC1 (NM_178040)

6.8+1.5

10.8+3.0

[Elks/rab6-interacting family member 1]*

  

TACC2 (NM_206862)

13.7+3.2

6.4+2.0

[Transforming, acidic coiled-coil containing protein 2]

  

ZBTB22 (NM_005453)

5.2+2.7

12.3+3.1

[Zinc finger and BTB domain containing 22]*

  

Proliferative phase

BAG5 (NM_001015049)

4.2+1.9

6.5+4.1

[Bcl2-associated athanogene 5]

  

CDCA3 (NM_031299)

3.9+1.5

9.9+6.6

[Cell division cycle associated 3]

  

EGR3 (NM_004430)

3.7+1.0

5.3+1.4

[Early growth response 3]*

  

FGFBP1 (NM_005130)

5.7+2.1

7.3+2.7

[Fibroblast growth factor binding protein 1]

  

TPM3 (NM_001043352)

3.4+1.9

6.3+3.4

[Tropomyosin 3]

  

Secretory phase

DHRS3 (NM_004753)

3.6+1.7

5.9+1.9

[Dehydrogenase/reductase (SDR family) member]

  

Up-regulated in ectopic tissue

  

General

  

BAP1 (NM_004656)

12.6+3.3

13.9+3.4

[BRCA1 associated protein-1]*

  

CBLL1 (NM_024814)

6.2+2.5

6.1+2.5

[Cas-Br-M (murine) ecotropic retroviral transforming sequence-like 1]

  

CLOCK (NM_004898)

9.0+2.6

5.3+0.6

[Clock homolog (mouse)]*

  

EPB41L1 (NM_012156)

3.1+1.6

2.6+1.2

[Erythrocyte membrane protein band 4.1-like 1]

  

LPL (NM_000237)

5.5+2.9

7.2+2.9

[Lipoprotein lipase]

  

PPAT (NM_002703)

5.8+2.9

5.6+3.4

[Phosphoribosyl pyrophosphate amidotransferase]

  

SCAMP1 (NM_004866)

10.5+3.2

6.0+2.6

[Secretory carrier membrane protein 1]

  

SFRS1 (NM_001078166)

8.7+3.6

6.6+2.2

[Splicing factor, arginine/serine-rich 1]

  

USP46 (NM_022832)

4.0+1.8

3.7+1.1

[Ubiquitin specific peptidase 46]

  

YWHAE (NM_006761)

3.4+2.7

3.3+1.8

[Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon]

  

ZNF644 (NM_201269)

4.4+1.0

5.1+2.9

[Zinc finger protein 644]

  
  1. aBetween eutopic and ectopic samples, shown as mean ± SD.
  2. bBased on GSEA implementation on DC results and their DE analysis (n = 18).
  3. cBased on transcript numbers from RT-PCR analysis of RNA samples from a different set of autologous paired eutopic and ectopic tissues (n = 8).
  4. *Genes selected in gene families identified in GSEA gene sets (see Table 5).