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Table 6 Selected genes expression of which bear predictable leads to ovarian endometriosis among Indian women

From: Genome-wide expressions in autologous eutopic and ectopic endometrium of fertile women with endometriosis

Expression characteristics
Gene symbol (GenBank ID) [Gene name] Fold changea
Microarrayb RT-PCRc
Up-regulated in eutopic tissue   
General   
3HMGN2 (NM_005517) 4.8+1.0 2.4++0.3
[High-mobility group nucleosomal binding domain 2]   
MKI67 (NM_002417 ) 3.4+0.9 4.6+1.8
[Ki-67-like antigen]   
NRCAM (NM_001037132) 4.5+1.6 2.1+0.5
[Neuronal cell adhesion molecule]*   
PARG (NM_003631) 3.8+2.1 3.4+1.5
[Poly (adp-ribose) glycohydrolase]   
TMPO (NM_001032283) 3.1+1.9 2.8+1.1
[Thymopoietin]   
Stage 3
ATP2A2 (NM_001681) 5.1+1.9 8.6+3.5
[ATPase, Ca++ transporting, cardiac muscle,slow twitch 2]   
CHIA (NM_021797) 3.4+1.3 7.3+1.5
[Chitinase, acidic]   
DAPK2 (NM_014326) 6.2+2.3 9.7+1.8
[Death-associated protein kinase 2]*   
ERC1 (NM_178040) 6.8+1.5 10.8+3.0
[Elks/rab6-interacting family member 1]*   
TACC2 (NM_206862) 13.7+3.2 6.4+2.0
[Transforming, acidic coiled-coil containing protein 2]   
ZBTB22 (NM_005453) 5.2+2.7 12.3+3.1
[Zinc finger and BTB domain containing 22]*   
Proliferative phase
BAG5 (NM_001015049) 4.2+1.9 6.5+4.1
[Bcl2-associated athanogene 5]   
CDCA3 (NM_031299) 3.9+1.5 9.9+6.6
[Cell division cycle associated 3]   
EGR3 (NM_004430) 3.7+1.0 5.3+1.4
[Early growth response 3]*   
FGFBP1 (NM_005130) 5.7+2.1 7.3+2.7
[Fibroblast growth factor binding protein 1]   
TPM3 (NM_001043352) 3.4+1.9 6.3+3.4
[Tropomyosin 3]   
Secretory phase
DHRS3 (NM_004753) 3.6+1.7 5.9+1.9
[Dehydrogenase/reductase (SDR family) member]   
Up-regulated in ectopic tissue   
General   
BAP1 (NM_004656) 12.6+3.3 13.9+3.4
[BRCA1 associated protein-1]*   
CBLL1 (NM_024814) 6.2+2.5 6.1+2.5
[Cas-Br-M (murine) ecotropic retroviral transforming sequence-like 1]   
CLOCK (NM_004898) 9.0+2.6 5.3+0.6
[Clock homolog (mouse)]*   
EPB41L1 (NM_012156) 3.1+1.6 2.6+1.2
[Erythrocyte membrane protein band 4.1-like 1]   
LPL (NM_000237) 5.5+2.9 7.2+2.9
[Lipoprotein lipase]   
PPAT (NM_002703) 5.8+2.9 5.6+3.4
[Phosphoribosyl pyrophosphate amidotransferase]   
SCAMP1 (NM_004866) 10.5+3.2 6.0+2.6
[Secretory carrier membrane protein 1]   
SFRS1 (NM_001078166) 8.7+3.6 6.6+2.2
[Splicing factor, arginine/serine-rich 1]   
USP46 (NM_022832) 4.0+1.8 3.7+1.1
[Ubiquitin specific peptidase 46]   
YWHAE (NM_006761) 3.4+2.7 3.3+1.8
[Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon]   
ZNF644 (NM_201269) 4.4+1.0 5.1+2.9
[Zinc finger protein 644]   
  1. aBetween eutopic and ectopic samples, shown as mean ± SD.
  2. bBased on GSEA implementation on DC results and their DE analysis (n = 18).
  3. cBased on transcript numbers from RT-PCR analysis of RNA samples from a different set of autologous paired eutopic and ectopic tissues (n = 8).
  4. *Genes selected in gene families identified in GSEA gene sets (see Table 5).