Table 2 Enriched common genes showing differential changes under different categories of comparisons a
Description of comparison (Number of genes) | Gene in enriched category (Gene symbol) | Enriched pathways | (p-value) |
|---|---|---|---|
Eutopic-to-ectopic | ERBB3 | Activation of astroglia proliferation | (0) |
Stage 3 & Stage 4 (3)b | Â | CDK5 mediated cell death and survival | (0) |
Proliferative & Secretory (4)b | Â | ERBB family signaling | (0) |
| Â | Â | Membrane bound ESR1 interaction with growth factor signaling | (<0.01) |
| Â | Â | Ligand-independent activation of ESR1 and ESR2 | (<0.01) |
| Â | ERBB3, LAMC2 | Alpha6/beta-4 integrins in carcinoma progression | (<0.01) |
Stages 3-to-4 | STAT2 | Immune response involving IL-15 and IFN signaling | (<0.02) |
Eutopic & Ectopic (50)c | |||
Proliferative-to-Secretory | Â | Angiotensin signaling via STATs | (<0.03) |
Eutopic & Ectopic (4)d | NOS1AP | nNOS signaling in neuronal process | (<0.03) |
| Â | AP1B1 | Immune response involving regulation of T cell function by CTLA-4 | (<0.04) |
| Â | SOCS5 | Immune response involving IL-4 signaling | (<0.04) |
| Â | GOT2 | GABA biosynthesis and metabolism | (<0.05) |