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Table 1 Patient characteristics in oocyte donors and infertility patients

From: Differences in ovarian aging patterns between races are associated with ovarian genotypes and sub-genotypes of the FMR1gene

 

Oocyte donors

Infertile patients

 

Total

Caucasian

African

Asian

Total

Caucasian

African

Asian

 

(n = 62)

(n = 46)

(n = 10)

(n = 6)

(n = 536)

(n = 373)

(n = 81)

(n = 82)

Age(years)

24.1 ± 3.71

24.2 ± 4.0

23.8 ± 2.2

23.7 ± 4.2

37.5 ± 5.21

37.8 ± 5.0

37.8 ± 5.3

36.1 ± 6.1

BMI(kg/m 2 )

21.0 ± 2.82

20.6 ± 2.6

22.3 ± 2.8

21.5 ± 4.1

24.5 ± 5.12

24.5 ± 5.3

26.8 ± 5.1

22.2 ± 3.1

Estradiol(pg/mL)

51.5 ± 26.1

52.5 ± 27.7

49.0 ± 19.4

46.2 ± 21.6

55.0 ± 37.8

57.0 ± 40.2

51.9 ± 34.5

48.8 ± 27.5

FSH(mIU/mL)

6.8 ± 2.93

6.7 ± 3.0

6.6 ± 1.5

8.2 ± 2.8

12.3 ±10.13

12.5 ± 10.2

13.8 ± 13.4

10.2 ± 4.1

AMH(ng/mL)

4.5 ± 2.94

4.3 ± 3.0

5.7 ± 1.9

4.6 ± 3.7

1.7 ± 2.24

1.6 ± 1.95

2.0 ± 2.9

2.3 ± 2.45

Oocyte yield

17.7 ± 7.76

16.7 ± 6.67

23.7 ± 10.47,8

14.8 ± 6.48

8.1 ± 6.76

8.1 ± 6.8

7.9 ± 7.3

8.1 ± 5.9

FMR1 n (%)

norm

33 (53.2)

26 (56.5)

4 (40.0)

3 (50.9)

315 (58.8)

218 (58.4)

41 (50.6)

56 (68.3)

het-norm/high

6 (9.7)

3 (6.5)

1 (10.0)

2 (33.3)

86 (16.0)

51 (13.7)

18 (22.2)

17 (20.7)

het-norm/low

19 (30.6)

14 (30.4)

5 (50.0)

0 (0.0)

107 (20.0)

83 (22.3)9

19 (23.5)9

5 (6.1)9

hom

4 (6.5)

3 (6.5)

0 (0.0)

1(16.7)

28 (5.2)

21 (5.6)

3 (3.7)

4 (4.9)

Primary infertility diagnosis n (%)

DOR

N/A

N/A

N/A

N/A

279 (52.1)

199 (47.5)

38 (47.5)

42 (51.2)

Male factor

N/A

N/A

N/A

N/A

134 (25.0)

96 (25.7)

18 (22.5)

20 (24.4)

Tubal Disease

N/A

N/A

N/A

N/A

105 (19.6)

70 (16.7)

23 (25.3)

12 (13.6)

Endometriosis

N/A

N/A

N/A

N/A

27 (5.0)

21 (5.6)

1 (1.3)

5 (6.1)

Uterine factors

N/A

N/A

N/A

N/A

36 (6.7)

20 (5.3)

1 (1.2)

15 (18.8)

PCOS

N/A

N/A

N/A

N/A

39 (7.3)

27 (7.2)

6 (7.5)

6 (7.3)

  1. Values are presented as means ± SD. Subscripts denote significant differences at P ≤ 0.05 (chi-square, t-tests and Holm-Sidak post hoc comparisons). 1 P = 0.001; 2 P = 0.001; 3 P = 0.001; 4 P = 0.001; 5 P = 0.007; 6 P = 0.001; 7 P = 0.008; 8 P = 0.022; 9 P = 0.012.