Figure 3From: Aberrant phenotypes of transgenic mice expressing dimeric human erythropoietinMorphological changes and histological analysis of the spleen in splenomegaly. A. Distinct splenomegaly-related changes were observed in the transgenic mice. The spleen weights of the transgenic mice were remarkably higher (21-fold increase in F1 and 11-fold increase in F2) than those of the control mice. B. Histological analysis of the spleen of the transgenic and control mice. Paraffin sections were stained with hematoxylin & eosin (original magnification, × 400).Back to article page