Figure 1

Expression of Src protein in rat ovaries during the activation and growth of primordial follicle were examined by immunohistochemistry analysis. Src protein expression in the oocyte and granulosa cell membrane of primordial and primary follicles (red arrows) is shown in A, B and C (which represent ovaries cultured in vitro for 0, 4 and 8 days, respectively). During the development of the follicles, the expression of Src protein increased corresponding. The negative controls are shown in D, E and F (which represent ovaries cultured in vitro for 0, 4 and 8 days, respectively).