Table 3 Cycle outcome measures
From: Addition of low dose hCG to rFSh benefits older women during ovarian stimulation for IVF
Group 1-A r FSH + Low dose hCG < 40 y N = 49 | Group 2-A r FSH < 40 y N = 67 | P Value | Group 1-B r FSH + Low dose hCG ≥ 40 y N = 39 | Group 2-B r FSH ≥ 40 y N = 32 | P Value | |
|---|---|---|---|---|---|---|
Starting dose of FSH | 246.43 ± 61.45 | 238.06 ± 71.96 | 0.501 | 302.56 ± 41.28 | 322.65 ± 60.03 | 0.114 |
Total dose of FSH. | 2,496 ± 774 | 2,284 ± 843 | 0.082 | 3,217 ± 874 | 3,264 ± 1,009 | 0.415 |
Treatment duration, days | 10.02 ± 1.73 | 9.45 ± 1.48 | 0.064 | 10.03 ± 1.58 | 9.40 ± 1.90 | 0.072 |
Need for dose change | 8/94 (8.5%) | 12/67 (17.9%) | 0.412 | 5/39 (12.8%) | 4/32 (12.5%) | 0.193 |
No of retrieved oocytes | 10.83 ± 6.55 | 12.50 ± 7.29 | 0.10 | 7.92 ± 4.32 | 6.28 ± 4.50 | 0.067 |
No of mature eggs | 9.49 ± 5.78 | 10.37 ± 6.55 | 0.230 | 5.72 ± 3.52 | 4.00 ± 3.34 | 0.019 |
No of fertilized eggs | 6.71 ± 4.43 | 7.35 ± 4.35 | 0.227 | 4.89 ± 2.74 | 3.70 ± 2.09 | 0.027 |
Fertilization rate per retrieved oocyte | 61.47% ± 18.38 | 62.97% ± 21.39 | 0.347 | 58.96% ± 19.48 | 58.72% ± 33.48 | 0.394 |
No of Embryos per transfer | 2.66 ± 1.22 | 2.68 ± 1.16 | 0.459 | 2.92 ± 1.09 | 3.00 ± 1.37 | 0.399 |
No of frozen embryos | 2.90 ± 3.66 | 4.14 ± 4.62 | 0.128 | 1.03 ± 2.13 | 0.296 ± 0.95 | 0.033 |
Total pregnancies per cycle started | 12/49 (24.49%) | 23/67 (34.33%) | 0.416 | 6/39 (15.38%) | 3/32 (9.38%) | 0.090 |
Total pregnancies per cycle completed | 12/45 (26.67%) | 23/60 (38.33%) | 0.152 | 6/38 (15.79%) | 3/27 (11.11%) | 0.588 |
Cancelled cycles | 3 | 2 | 0 | 4 | ||
Hyper stimulation | 0 | 5 | 0 | 0 | ||
No eggs retrieved | 1 | 0 | 1 | 1 |