Lessons from elective in vitro fertilization (IVF) in, principally, non-infertile women

Table 3 Patient/cycle characteristics for case–control study

	PGS Group	Control Group
n IVF cycles	30	30
Age (years)	38.7 ± 4.0	39.2 ± 4.0
Range	27.1–45.0	27.7–45.4
AMH (ng/mL)	1.5 ± 1.4	1.4 ± 1.8
Total gonadotropin dosage (IU) ²	4840 ± 1825	5934 ± 2330
Oocyte yields (n)	9.7 ± 5.6	9.7 ± 5.4
Range	2–25	2–25
Embryos transferred (n) ¹	1.6 ± 0.8	2.9 ± 1.0
Implantation rate (%) ³	26.4	9.5
Heartbeats/Embryos transferred	14/53	9/95
Pregnancy rate (%) ⁴	36.4	21.2
n	12/33	7/33
Miscarriage rate (%)	8.3	14.3
n	1/12	1/7

¹ Controls had significantly more embryo transferred (P < 0.0001), and ² utilized marginally more total gonadotropins (P = 0.046). ³ The implantation rate was significantly higher in PGS cycles (P = 0.008). ⁴ In univariate analyses pregnancy rates and miscarriage rates did not differ significantly. After appropriate adjustments, logistic regression analysis demonstrated 4.58-times the odds of clinical pregnancy after PGS than in controls (95% CI 1.102 to 19.060, Exp 4.584; P = 0.036).

ISSN: 1477-7827