Table 4 Frequencies of the epithelial expression levels of GPER (nuclear and cytoplasmic) and the classical sex hormone receptors in different types of endometriosis
Receptor | Expression level | Ovarian Endometriosis | Peritoneal Endometriosis | Deep infiltrating Endometriosis | p-value |
|---|---|---|---|---|---|
GPER cyt | High | 14/20 (70.0%) | 9/18 (50.0%) | 7/22 (31.8%) | 0.01 |
| Â | Low | 6/20 (30.0%) | 9/18 (50.0%) | 15/22 (68.2%) | Â |
GPER nuc | High | 16/20 (80.0%) | 13/18 (72.2%) | 13/22 (59.1%) | 0.2 |
| Â | Low | 4/20 (20.0%) | 5/18 (27.8%) | 9/22 (40.9%) | Â |
ER-alpha | High | 18/23 (78.3%) | 17/17 (100%) | 22/23 (95.7%) | 0.02 |
| Â | Low | 5/23 (21.7%) | 0/17 | 1/23 (4.3%) | Â |
ER-beta | High | 11/24 (45.8%) | 15/17 (88.2%) | 9/24 (37.5%) | 0.001 |
| Â | Low | 13/24 (54.2%) | 2/17 (11.8%) | 15/24 (62.5%) | Â |
PR | High | 8/21 (38.1%) | 16/17 (94.1%) | 18/22 (81.8%) | <0.001 |
| Â | Low | 13/21 (61.9%) | 1/17 (5.9%) | 4/22 (18.2%) | Â |