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Table 1 Mean immunoreactivity scores of the expression of GPER, ER alpha, ER beta and PR in the epithelium and stroma of normal endometrium and different endometriosis types

From: Expression of the G protein-coupled estrogen receptor (GPER) in endometriosis: a tissue microarray study

 

Normal Endometrium

Ovarian Endometriosis

Peritoneal Endometriosis

Deep-Infiltrating Endometriosis

Epithelium

    

GPER cyt

1.2 (±1.7, 0–4)

6.5 (±3.5, 0–12)

5.0 (±3.7, 0–10)

4.0 (±2.8, 0–8)

GPER nuc

6.4 (±2.6, 0–12)

6.9 (±1.8, 3–8)

8.5 (±3.8, 2–12)

5.4 (±2.2, 2–12)

ER alpha

10.6 (±2.4, 3–12)

8.6 (±3.5, 2–12)

11.4 (±1.6, 6–12)

9.8 (±2.7, 3–12)

ER beta

2.4 (±2.2, 0–8)

5.4 (±2.6, 0–10)

7.4 (±1.5, 4–10)

4.5 (±2.5, 0–8)

PR

11.5 (±1.7, 3–12)

4.6 (±4.3, 0–12)

10.9 (±2.4, 3–12)

9.2 (±3.7, 2–12)

Stroma

    

GPER nuc

7.7 (±3.0, 2–12)

10.7 (±1.6, 8–12)

11.7 (±0.8, 9–12)

10.1 (±1.9, 6–12)

ER alpha

8.7 (±3.1, 2–12)

10.6 (±2.1, 6–12)

11.3 (±1.6, 6–12)

10.1 (±3.0, 2–12)

ER beta

1.8 (±2.0, 0–8)

5.4 (±2.3, 0–10)

7.6 (±1.3, 4–10)

3.9 (±2.3, 0–8)

PR

11.7 (±0.9, 8–12)

11 (±1.4, 8–12)

10.4 (±2.5, 3–12)

11 (±2.1, 4–12)

  1. Values are represented as mean immunoreactivity scores (IRS) (±standard deviation, range). GPER G protein-coupled estrogen receptor (cyt cytoplasmic, nuc nuclear staining), ER estrogen receptor, PR progesterone receptor. No cytoplasmic GPER expression was detected in the stroma of endometrium and endometriosis.