Table 1 Summary of Select Chemokines

BCA-1

lymphoid tissue

B-lymphocytes

CXCR5

ENA-78

epithelial cells

neutrophils

CXCR2

GCP-2

granulocytes

neutrophils

CXCR1

GRO-αβγ

endothelial cells, fibroblasts, monocytes, macrophages

neutrophils

CXCR2

IL-8

macrophages, endothelial cells

neutrophils, basophils, T-lymphocytes, epithelial cells, macrophages

CXCR1, R2

IP-10

monocytes

T-lymphocytes, TIL, endothelial cells, NK cells

CXCR3

MIG

monocytes, macrophages

T-lymphocytes, TIL

CXCR3

SDF-1α, 1β

stromal cells

hematopoietic cells

CXCR4

-CC-Chemokines

Chemokine

Source

Primary Target

Receptor

Eotaxin

monocytes

eosinophils

CCR3

Exodus-1

neutrophils, peripheral blood lymphocytes

T-lymphocytes, NK cells

CCR6

MCP-1

endothelial cells, monocytes, macrophages, fibroblasts

monocytes, basophils NK cells, T-lymphocytes

CCR2, R4, R10

MCP-2

monocytes, macrophages

monocytes, basophils, eosinophils, NK cells, T-lymphocytes

CCR1, R2, R3 R10

MCP-3

monocytes, macrophages

monocytes, basophils, eosinophils, NK cells, T-lymphocytes, dendritic cells

CCR1, R2 R3, R10

MCP-4

endothelial cells, monocytes, macrophages

monocytes, T-lymphocytes, eosinophils

CCR3

MIP-1α

monocytes, T-lymphocytes, neutrophils

monocytes, T-lymphocytes, NK cells, basophils, eosinophils, dendritic cells

CCR1, R4,

MIP-1β

monocytes, neutrophils

monocytes, T-cells, NKs, dendritic cells

CCR5

MIP-5

monocytes

monocytes, eosinophils, basophils

CCR1, R3

RANTES

T-lymphocytes

T-lymphocytes, NK cells, basophils, eosinophils, dendritic cells

CCR1, R3, R4, R5, R10

TARC

monocytes, thymus tissue

T-lymphocytes

CCR4

-C-Chemokine

Chemokine

Source

Primary Target

Receptor

Lymphotactin

T-lymphocytes, NK cells

T-lymphocytes, B-lymphocytes, neutrophils, NK cells

XCR1

-CX3C-Chemokine

Chemokine

Source

Primary Target

Receptor

Fractalkine

macrophages, dendritic cells, epithelial cells

NK cells

CX3CR1