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Table 4 Inhibition of sperm mobility by specific COX-1 and COX-2 inhibitors1

From: Prostaglandin levels in seminal plasma and sperm extracts of the domestic turkey, and the effects of cyclooxygenase inhibitors on sperm mobility

Dose Level (mM)

Resveratrol (COX-1 Inhibitor)

NS-398 (COX-2 Inhibitor)

0.0 (Control)

100a

100a

0.1

61.7 ± 2.3b

55.7 ± 5.4b

1.0

20.0 ± 3.4c

2.1 ± 1.4d

10.0

2.2 ± 1.3d

15.0 ± 2.3c

  1. 1Mean ± SEM. Values are expressed as the percentage of the Control which contained no drug (Control = 100%). a-d Within columns, values without common superscript differ significantly (P ≤ 0.05; n = 3).
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Reproductive Biology and Endocrinology

ISSN: 1477-7827

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