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Table 1 Effects of ICI 182,780 on body and testis weight.a

From: The antiestrogen ICI 182,780 induces early effects on the adult male mouse reproductive tract and long-term decreased fertility without testicular atrophy

   

Testis Weight (mg)

Day of treatment

Body Control

Weight (g) ICI-Treated

Control

ICI-Treated

8

17.99 ± 2.22

19.8 ± 1.17

71.4 ± 1.81

83.2 ± 5.87

10

16.48 ± 0.81

22.66 ± 0.42

68.0 ± 2.96

78.9 ± 4.33

12

19.74 ± 1.58

24.41 ± 1.43

85.1 ± 2.49

90.9 ± 0.86

14

22.17 ± 0.98

21.57 ± 0.15

91.0 ± 3.40

91.0 ± 2.93

16

22.65 ± 0.46

24.3 ± 0.15

84.9 ± 1.40

96.3 ± 1.70b

25

25.67 ± 0.66

26.11 ± 0.56

96.5 ± 2.59

94.6 ± 2.85

59

26.63 ± 0.44

30.19 ± 1.27

128.7 ± 5.37

105.0 ± 7.03b

125

29.97 ± 0.45

31.97 ± 0.78

95.2 ± 2.58

74.8 ± 4.75b

  1. a Values are mean ± SEM b p < 0.05.
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Reproductive Biology and Endocrinology

ISSN: 1477-7827

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