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Figure 3 | Reproductive Biology and Endocrinology

Figure 3

From: Multiple luteinizing hormone receptor (LHR) protein variants, interspecies reactivity of anti-LHR mAb clone 3B5, subcellular localization of LHR in human placenta, pelvic floor and brain, and possible role for LHR in the development of abnormal pregnancy, pelvic floor disorders and Alzheimer's disease

Figure 3

LHR immunostaining in porcine tissues. A–C) Preovulatory follicles (late follicular phase) show a transition from granular cytoplasmic to surface LHR immunoreactivity in granulosa cells (arrowheads), lack of staining of vascular layer, increase of LHR staining in theca interna and extreme dilatation of follicular microvasculature (v). D) Control for C. E) Mature CL. F) Old CL. G) Ovarian surface epithelium (arrowhead). H) Fallopian tube (FT). I) Skin vessels show strong LHR immunoreactivity of the entire vascular wall (arrowhead). J) In ovarian vasculature, the LHR immunoreactivity is limited to the nuclei of some endothelial cells (arrowhead) but other components of vascular wall are unstained. Insets in E–J show control staining. Details in text. Hematoxylin counterstain except panels A–D, H and I.

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Reproductive Biology and Endocrinology

ISSN: 1477-7827

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