Figure 3

In situ hybridization studies showing 3β-hydroxysteroid dehydrogenase (3βHSD) type VI and prostaglandin D (PGD)-synthetase expression in adult control GnRH-null mice and GnRH-null mice following injection with hCG. Hybridisation of 3βHSD VI anti-sense probe to control GnRH-null testis is shown in A) and at higher power in B). In C) hybridisation to testes from GnRH-null mice after 4 injections of hCG is shown. Hybridisation to a sense 3βHSD VI probe is shown in D). Hybridisation of an anti-sense PGD-synthetase probe to testis from control GnRH-null mice is shown in E) while hybridization of a sense probe is shown in F).