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  1. Potassium channels are important for the structure and function of the spermatozoa. As a potassium transporter, the mSlo3 is essential for male fertility as Slo3 knockout male mice were infertile with the series ...

    Authors: Mingrong Lv, Chunyu Liu, Chunjie Ma, Hui Yu, Zhongmei Shao, Yang Gao, Yiyuan Liu, Huan Wu, Dongdong Tang, Qing Tan, Junqiang Zhang, Kuokuo Li, Chuan Xu, Hao Geng, Jingjing Zhang, Hang Li…
    Citation: Reproductive Biology and Endocrinology 2022 20:5
  2. Insulin resistance (IR) contributes to ovarian dysfunctions in polycystic ovarian syndrome (PCOS) patients. Serum amyloid A1 (SAA1) is an acute phase protein produced primarily by the liver in response to infl...

    Authors: Qinling Zhu, Yue Yao, Lizhen Xu, Hasiximuke Wu, Wangsheng Wang, Yaqiong He, Yuan Wang, Yao Lu, Jia Qi, Ying Ding, Xinyu Li, Jiaan Huang, Hanting Zhao, Yanzhi Du, Kang Sun and Yun Sun
    Citation: Reproductive Biology and Endocrinology 2022 20:4
  3. Successful implantation is dependent on coordination between maternal endometrium and embryo, and the role of EVs in the required cross-talk cell-to-cell has been recently established. In this regard, it has b...

    Authors: Marina Segura-Benítez, María Cristina Carbajo-García, Ana Corachán, Amparo Faus, Antonio Pellicer and Hortensia Ferrero
    Citation: Reproductive Biology and Endocrinology 2022 20:3
  4. Women with uterine adenomyosis seeking assisted reproduction have been associated with compromised endometrial receptivity to embryo implantation. To understand the mechanisms involved in this process, we aime...

    Authors: Erika Prašnikar, Tanja Kunej, Mario Gorenjak, Uroš Potočnik, Borut Kovačič and Jure Knez
    Citation: Reproductive Biology and Endocrinology 2022 20:2
  5. Several clinical studies showed that statins were potential to treat polycystic ovary syndrome (PCOS). Through comprehensive search PubMed, EMBASE, the Web of Science, BIOSIS, the ClinialTrails.gov, and the Co...

    Authors: Jianguo Chen, Chaoran Huang, Tongtong Zhang, Wuqing Gong, Xiaofeng Deng, Hua Liu, Jinbo Liu and Yuanbiao Guo
    Citation: Reproductive Biology and Endocrinology 2021 19:189

    The Correction to this article has been published in Reproductive Biology and Endocrinology 2022 20:66

  6. To investigate the role of adenosine monophosphate (AMP)-activated protein kinase (AMPK) on the production of interleukin (IL)-8, monocyte chemoattractant protein (MCP)-1, prostaglandin E2 and F2α induced by I...

    Authors: Yasushi Kawano, Hatsumi Sato, Kaori Goto, Masakazu Nishida and Kaei Nasu
    Citation: Reproductive Biology and Endocrinology 2021 19:188
  7. Recurrent implantation failure (RIF) is a major limitation of assisted reproductive technology, which is associated with impaired endometrial receptivity. Although N6-methyladenosine (m6A) has been demonstrated t...

    Authors: Pingping Xue, Wenbo Zhou, Wenqiang Fan, Jianya Jiang, Chengcai Kong, Wei Zhou, Jianmei Zhou, Xiaoyang Huang, Haiyan Yang, Qian Han, Bin Zhang, Lingyun Xu, Bin Yu and Li Chen
    Citation: Reproductive Biology and Endocrinology 2021 19:187
  8. The goal of this study was to investigate which factors, excluding embryo aneuploidies, are associated with miscarriage in patients who have undergone a single euploid blastocyst transfer.

    Authors: María del Carmen Nogales, María Cruz, Silvia de Frutos, Eva María Martínez, María Gaytán, Marta Ariza, Fernando Bronet and Juan A. Garcia-Velasco
    Citation: Reproductive Biology and Endocrinology 2021 19:186
  9. For the association between time-lapse technology (TLT) and embryo ploidy status, there has not yet been fully understood. TLT has the characteristics of large amount of data and non-invasiveness. If we want t...

    Authors: Bo Huang, Wei Tan, Zhou Li and Lei Jin
    Citation: Reproductive Biology and Endocrinology 2021 19:185
  10. Polycystic ovary syndrome (PCOS) is a common endocrine disorder with the disorders of estrogen(E2) and progesterone(P) secretion. The purpose of this study was to evaluate the association between the progester...

    Authors: Yiqing Yang, Bowen Liu, Gengxiang Wu and Jing Yang
    Citation: Reproductive Biology and Endocrinology 2021 19:184
  11. To improve the developmental competence of in vitro cultured oocytes, extensive literature focused on maturation rate improvement with different additives in culture medium, while studies investigating the mat...

    Authors: Qiyu Yang, Lixia Zhu, Meng Wang, Bo Huang, Zhou Li, Juan Hu, Qingsong Xi, Jing Liu and Lei Jin
    Citation: Reproductive Biology and Endocrinology 2021 19:183
  12. Luteinizing hormone (LH) and human chorionic gonadotropin (hCG) activate distinct intracellular signaling cascades. However, due to their similar structure and common receptor, they are used interchangeably du...

    Authors: M. Kirshenbaum, O. Gil, J. Haas, R. Nahum, E. Zilberberg, O. Lebovitz and R. Orvieto
    Citation: Reproductive Biology and Endocrinology 2021 19:182
  13. The quality of the early embryo is vital to embryonic development and implantation. As a highly conserved serine/threonine kinase, p21-activated kinase 2 (Pak2) participates in diverse biologic processes, espe...

    Authors: Juan Zeng, Nengqing Liu, Yinghong Yang, Yi Cheng, Yuanshuai Li, Xiaoxia Guo, Qian Luo, Lifen Zhu, Hongmei Guan, Bing Song and Xiaofang Sun
    Citation: Reproductive Biology and Endocrinology 2021 19:181
  14. MicroRNAs (miRNAs) are small, non-coding RNAs that are dysregulated in many diseases and can act as biomarkers. Although well-studied in cancer, the role of miRNAs in embryo implantation is poorly understood. ...

    Authors: Hong Zeng, Yu Fu, Lang Shen and Song Quan
    Citation: Reproductive Biology and Endocrinology 2021 19:180
  15. Ovarian endometrioma is a common gynecological disease that is often treated with surgery or hormonal treatment. Ovarian cystectomy, a surgical procedure for ovarian endometrioma, can result in impaired ovaria...

    Authors: Ayako Muraoka, Satoko Osuka, Atsushi Yabuki, Bayasula, Masato Yoshihara, Hideaki Tanaka, Reina Sonehara, Natsuki Miyake, Mayuko Murakami, Sayako Yoshita, Natsuki Nakanishi, Tomoko Nakamura, Maki Goto, Akira Iwase and Hiroaki Kajiyama
    Citation: Reproductive Biology and Endocrinology 2021 19:179
  16. Ovarian cancer is the leading cause of death in patients with gynecologic cancer, and circular RNAs (circRNAs) are involved in cancer progression. However, there are limited studies on the roles of circRNAs in...

    Authors: Yuping Du, Xin Liu, Song Zhang, Shuo Chen, Xue Guan, Qianhui Li, Xi Chen and Yang Zhao
    Citation: Reproductive Biology and Endocrinology 2021 19:176
  17. Immune dysfunction is one of the mechanisms to promote polycystic ovary syndrome (PCOS). Various immune cells have been reported to be involved in the development of PCOS. Meanwhile, the disturbance of metabol...

    Authors: Mengting Zhu, Yuping Xu, Caihua Li, Zhimin Lu, Kaihuan Bi, Kangxia Wang, Peipei Guo, Huanhuan Jiang and Yunxia Cao
    Citation: Reproductive Biology and Endocrinology 2021 19:175
  18. Assisted reproductive technology (ART) insurance mandates promote more selective utilization of ART clinic resources including intracytoplasmic sperm injection (ICSI). Our objective was to examine whether ICSI...

    Authors: Pavel Zagadailov, Kyung S. Cho and David B. Seifer
    Citation: Reproductive Biology and Endocrinology 2021 19:174
  19. Bone morphogenetic protein 2 (BMP2), growth differentiation factor 8 (GDF8) and their functional receptors are expressed in human ovarian follicles, and these two intrafollicular factors play essential roles i...

    Authors: Xiaoyan Luo, Hsun-Ming Chang, Yuyin Yi, Yingpu Sun and Peter C. K. Leung
    Citation: Reproductive Biology and Endocrinology 2021 19:173
  20. Information regarding the influence of cytoplasmic events during fertilisation on the clinical outcome remains limited. The cytoplasmic halo is one of these events. A previous study that used time-lapse techno...

    Authors: Kenji Ezoe, Tetsuya Miki, Tadashi Okimura, Kazuo Uchiyama, Akiko Yabuuchi, Tamotsu Kobayashi and Keiichi Kato
    Citation: Reproductive Biology and Endocrinology 2021 19:172
  21. With the increased use of assisted reproductive technology (ART), assessing the potential health risks of children conceived on ART important to public health. Most research in this area has focused on the eff...

    Authors: Xin Xu, Han Wu, Yuehong Bian, Linlin Cui, Yuanyuan Man, Zhao Wang, Xin Zhang, Changming Zhang and Ling Geng
    Citation: Reproductive Biology and Endocrinology 2021 19:171
  22. Polycystic ovary syndrome (PCOS) is an endocrine-related follicular developmental disorder that affects 50 %-70 % of reproductive-aged women diagnosed with ovulation-related infertility. Abnormal proliferation...

    Authors: Yi-xuan Wu, Yan-shan Lin, Si-chen Li, Xi Yao, Mingwei Cheng, Lin Zhu and Hai-ying Liu
    Citation: Reproductive Biology and Endocrinology 2021 19:170
  23. Authors: Marzieh Farimani, Arash Nazari, Shahrzad Mohammadi and Roghayeh Anvari Aliabad
    Citation: Reproductive Biology and Endocrinology 2021 19:169

    The original article was published in Reproductive Biology and Endocrinology 2021 19:137

  24. Diabetes mellitus (DM), a chronic metabolic disease, severely impairs male reproductive function. However, the underpinning mechanisms are still incompletely defined, and there are no effective strategies or m...

    Authors: Weiguo He, Huiqing Liu, Linlin Hu, Yaohui Wang, Lane Huang, Aihong Liang, Xuan Wang, Qing Zhang, Yi Chen, Yi Cao, Suyun Li, Junli Wang and Xiaocan Lei
    Citation: Reproductive Biology and Endocrinology 2021 19:168
  25. Polycystic ovary syndrome (PCOS) is a common endocrine and metabolic disease in women at childbearing age. Several circular RNAs (circRNAs) have been demonstrated to be involved in PCOS. In this study, we aime...

    Authors: Lishuang Xu, Fang Xiong, Yinyang Bai, Juxia Xiao, Yun Zhang, Jie Chen and Qiuping Li
    Citation: Reproductive Biology and Endocrinology 2021 19:167
  26. Maternal metabolic disorders are linked to reduced metabolic health and oocyte quality. Obese women are advised to lose weight before conception to increase pregnancy chances. However, as human studies show no...

    Authors: Anouk Smits, Waleed F. A. Marei, Diane De Neubourg and Jo L. M. R. Leroy
    Citation: Reproductive Biology and Endocrinology 2021 19:166
  27. Progesterone supplementation is widely performed in women with threatened miscarriage or a history of recurrent miscarriage; however, the effects of early progesterone supplementation on pregnancy-related comp...

    Authors: Hanglin Wu, Songying Zhang, Xiaona Lin, Jing He, Shasha Wang and Ping Zhou
    Citation: Reproductive Biology and Endocrinology 2021 19:165
  28. Pregnancies with > 1 corpus luteum (CL) display a hyperdynamic circulation and an increased risk of small-for-gestational age deliveries. Among the factors released by the CL is prorenin, the inactive precurso...

    Authors: Rosalieke E. Wiegel, Maud J. H. Karsten, Igna F. Reijnders, Lenie van Rossem, Sten P. Willemsen, Annemarie G. M. G. J. Mulders, Anton H. J. Koning, Eric A. P. Steegers, A. H. Jan Danser and Régine P. M. Steegers-Theunissen
    Citation: Reproductive Biology and Endocrinology 2021 19:164
  29. The application of artificial oocyte activation (AOA) after intracytoplasmic sperm injection (ICSI) is successful in mitigating fertilization failure problems in assisted reproductive technology (ART). Neverth...

    Authors: Mingru Yin, Weina Yu, Wenzhi Li, Qianqian Zhu, Hui Long, Pengcheng Kong and Qifeng Lyu
    Citation: Reproductive Biology and Endocrinology 2021 19:163
  30. Endometriosis, the presence of active endometrial tissue outside the lining membrane of the uterine cavity, is a common disease in women of childbearing age. The ectopic endometrium has some characteristics of...

    Authors: Liya Shi, Xue Xue, Hui Tian, Hongjuan Ye, Hui Wang, Rongxiang Wang, Yu Liu, Caixia Zhang, Qiuju Chen and Lihua Sun
    Citation: Reproductive Biology and Endocrinology 2021 19:161
  31. Infertility associated with endometriosis can be explained by several non-exclusive mechanisms. The oocyte plays a crucial role in determining embryonic competence and this is particularly relevant for in vitr...

    Authors: Camille Robin, Audrey Uk, Christine Decanter, Hélène Behal, Pierre Collinet, Chrystèle Rubod, Anne-Laure Barbotin and Geoffroy Robin
    Citation: Reproductive Biology and Endocrinology 2021 19:160
  32. Azoospermic patients have benefited from both epididymal and testicular spermatozoa intracytoplasmic sperm injection (ICSI) treatment and lasers have been used to identify viable, immotile spermatozoa before t...

    Authors: Huanhua Chen, Caizhu Wang, Hong Zhou, Jinhui Shu, Xianyou Gan, Kongrong Xu, Zhulian Wu, Xihe Deng, Guiting Huang and Ruoyun Lin
    Citation: Reproductive Biology and Endocrinology 2021 19:159
  33. Synchronization of follicles is key to improving ovulation stimulation with the gonadotropin-releasing hormone (GnRH) antagonist protocol. GnRH antagonist administration in the early follicular phase can quick...

    Authors: Yisheng Zhang, Liling Liu, Jie Qin, Hongyi Huang, Lintao Xue, Shikai Wang and Weihong Tan
    Citation: Reproductive Biology and Endocrinology 2021 19:158
  34. Infertility, an important source of stress, could affect sexual life. Extensive studies suggest that the incidence of sexual dysfunction is highly prevalent in infertile women. As the duration of infertility i...

    Authors: Meng Dong, Xiaoyan Xu, Yining Li, Yixian Wang, Zhuo Jin and Jichun Tan
    Citation: Reproductive Biology and Endocrinology 2021 19:157
  35. Human papillomavirus (HPV) has been shown to adversely affect human reproduction. We aimed to evaluate the prevalence of human papillomavirus (HPV) infection in men and its correlation with semen parameters an...

    Authors: Hana Jaworek, Vladimira Koudelakova, Ivana Oborna, Blazena Zborilova, Jana Brezinova, Dagmar Ruzickova, Jana Vrbkova, Pavla Kourilova and Marian Hajduch
    Citation: Reproductive Biology and Endocrinology 2021 19:156
  36. Embryo cryopreservation is a widely used technique in infertility management and today is an essential part of assisted reproductive technology (ART). In some cases, re-vitrification can be applied to good qua...

    Authors: Maryam Daneshvar, Mansoureh Movahedin, Mohammad Salehi and Mehrdad Noruzinia
    Citation: Reproductive Biology and Endocrinology 2021 19:155
  37. To investigate whether the endometrial thickness change ratio from the progesterone administration day to the blastocyst transfer day is associated with pregnancy outcomes in a single frozen-thawed euploid bla...

    Authors: Ziqi Jin, Jingdi Li, EnTong Yang, Hao Shi, Zhiqin Bu, Wenbin Niu, Fang Wang, Mingzhu Huo, Hui Song and YiLe Zhang
    Citation: Reproductive Biology and Endocrinology 2021 19:154
  38. Gynecologic oncologists should be aware of the option of conception through IVF/PGT-M for families with high BRCA related morbidity or mortality. Our objective was to investigate the cost-effectiveness of prei...

    Authors: Nadav Michaan, Moshe Leshno, Yoni Cohen, Tamar Safra, Shira Peleg-Hasson, Ido Laskov and Dan Grisaru
    Citation: Reproductive Biology and Endocrinology 2021 19:153
  39. There are two major management approach for cornual heterotopic pregnancy, transvaginal cornual embryo reduction with ultrasound guidance, or laparoscopic cornual resection. This no consensus on the optimal ma...

    Authors: Sichen Li, Mingzhu Cao, Hanyan Liu, Yuxia He and Jianqiao Liu
    Citation: Reproductive Biology and Endocrinology 2021 19:152
  40. There is evidence to suggest that long term exposure to air pollution could be associated with decreased levels of fertility, although there is controversy as to how short term exposure may compromise fertilit...

    Authors: Mireia González-Comadran, Bénédicte Jacquemin, Marta Cirach, Rafael Lafuente, Thomas Cole-Hunter, Mark Nieuwenhuijsen, Mario Brassesco, Buenaventura Coroleu and Miguel Angel Checa
    Citation: Reproductive Biology and Endocrinology 2021 19:151
  41. Advanced glycation end-products (AGE), which accumulate with insulin resistance and aging, impair folliculogenesis and may decrease endometrial receptivity. Hishi (Trapa bispinosa Roxb.) extract, a safe herbal me...

    Authors: Masao Jinno, Ryoji Nagai, Masayoshi Takeuchi, Aiko Watanabe, Koji Teruya, Hikari Sugawa, Naohisa Hatakeyama and Yuichi Jinno
    Citation: Reproductive Biology and Endocrinology 2021 19:149
  42. Recently, human infertility incidence is increasing in obese women causing it to become an emerging global health challenge requiring improved treatment. There is extensive evidence that obesity caused female ...

    Authors: Xiuxiu Gao, Yangyang Li, Zhuoyao Ma, Jia Jing, Zhengqing Zhang, Yue Liu and Zhide Ding
    Citation: Reproductive Biology and Endocrinology 2021 19:148
  43. Polycystic ovary syndrome (PCOS), as the most common endocrine disorder in reproductive-aged women, is characterized by oxidative stress and ovarian tissue inflammation. Green tea extract (GTE) potentially pos...

    Authors: Vahid Maleki, Ehsaneh Taheri, Parisa Varshosaz, Fatemeh Pourteymour Fard Tabrizi, Jalal Moludi, Hamed Jafari-Vayghan, Mahdi Shadnoush, Seyed Hossein Yahyazadeh Jabbari, Mehri Seifoleslami and Mohammad Alizadeh
    Citation: Reproductive Biology and Endocrinology 2021 19:147
  44. Phthalates such as di (2-ethylhexyl) phthalate (DEHP) are well known exogenous substances, disrupting reproductive system function and structure. The current research demonstrated the effect of ellagic acid (E...

    Authors: Azam Hosseinzadeh, Saeed Mehrzadi, Amir Siahpoosh, Zahra Basir, Nosrat Bahrami and Mehdi Goudarzi
    Citation: Reproductive Biology and Endocrinology 2021 19:146
  45. Overweight and obesity affect millions of people globally, which has also serious implications for reproduction. For example, treatment outcomes after in vitro fertilisation (IVF) are worse in women with a hig...

    Authors: Linette van Duijn, Melek Rousian, Jeffrey Hoek, Sten P. Willemsen, Eva S. van Marion, Joop S. E. Laven, Esther B. Baart and Régine P. M. Steegers-Theunissen
    Citation: Reproductive Biology and Endocrinology 2021 19:145
  46. In mammals, germline development undergoes dramatic morphological and molecular changes and is epigenetically subject to intricate yet exquisite regulation. Which epigenetic players and how they participate in...

    Authors: Xue Jiang, Xiaoli Zhu, Yu Cheng, Muhammad Azhar, Xuemei Xing, Wenqing Li, Yuzhu Cao, Qinghua Shi and Jianqiang Bao
    Citation: Reproductive Biology and Endocrinology 2021 19:144

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