Age < 35 | Cleavage-stage embryo transfer | |||||
Variable | Before matching | After matching | ||||
SET- GQE (N = 143) | DET- GQE + PQE (N = 224) | P value | SET- GQE (N = 113) | DET- GQE + PQE (N = 113) | P value | |
Implantation n (%) | 62 (43.4) | 131 (29.2) | 0.002 | 49 (43.4) | 70 (31.0) | 0.024 |
OR (95%CI) | Reference | 0.546 (0.355—0.839) | 0.006 | Reference | 0.577 (0.354—0.939) | 0.027 |
Clinical Pregnancy n (%) | 61 (42.7) | 104 (46.4) | 0.479 | 48 (42.5) | 55 (48.7) | 0.350 |
OR (95%CI) | Reference | 1.210 (0.750—1.954) | 0.434 | Reference | 1.264 (0.742—2.151) | 0.389 |
Live birth n (%) | 51 (35.7) | 89 (39.7) | 0.434 | 42 (37.2) | 47 (41.6) | 0.496 |
OR (95%CI) | Reference | 1.137 (0.695—1.860) | 0.609 | Reference | 1.227 (0.719—2.092) | 0.454 |
Multiple birth n (%) | 4 (7.8) | 22 (24.7) | 0.013 | 3 (7.1) | 12 (25.5) | 0.021 |
OR (95%CI) | Reference | 4.421 (1.102—17.732) | 0.036 | Reference | 4.724 (1.121—19.913) | 0.034 |
Miscarriage n (%) | 10 (16.4) | 15 (14.4) | 0.733 | 6 (12.5) | 8 (14.5) | 0.763 |
OR (95%CI) | Reference | 0.921 (0.444—1.909) | 0.824 | Reference | 0.418 (0.085—2.052) | 0.283 |
Preterm birth n (%) | 6 (11.8) | 13 (14.6) | 0.637 | 5 (11.9) | 5 (10.6) | 1.000 |
OR (95%CI) | Reference | 1.232 (0.429—3.539) | 0.698 | Reference | 0.890 (0.222—3.577) | 0.870 |
Gestational age (weeks) | 38.6 ± 1.7 | 38.1 ± 2.2 | 0.146 | 38.6 ± 1.9 | 38.3 ± 1.9 | 0.473 |
OR (95%CI) | Reference | 0.682 (0.354—1.313) | 0.252 | Reference | 0.813 (0.383—1.726) | 0.590 |
Birth height (mm) | 49.5 ± 2.1 | 49.1 ± 2.3 | 0.271 | 49.5 ± 2.2 | 49.2 ± 1.7 | 0.466 |
OR (95%CI) | Reference | 0.673 (0.348—1.301) | 0.239 | Reference | 0.818 (0.401—1.668) | 0.580 |
Birth weight (g) | 3116.2 ± 541.7 | 2977.0 ± 597.9 | 0.148 | 3128.7 ± 564.1 | 2974.6 ± 577.6 | 0.176 |
OR (95%CI) | Reference | 0.964 (0.910—1.022) | 0.218 | Reference | 0.965 (0.898—1.037) | 0.336 |
Low birth weight n (%) | 9 (16.4) | 26 (23.4) | 0.294 | 8 (17.8) | 15 (25.4) | 0.352 |
OR (95%CI) | Reference | 1.867 (0.623—5.594) | 0.265 | Reference | 1.722 (0.528—5.610) | 0.367 |
Congenital anomalies n (%) | 1 (1.8) | 2 (1.8) | 1.000 | 1 (2.2) | 2 (3.4) | 1.000 |
OR (95%CI) | - | - | - | Reference | 1.384 (0.116- 16.454) | 0.797 |
Age ≥ 35 | Cleavage-stage embryo transfer | |||||
Variable | Before matching | After matching | ||||
SET- GQE (N = 58) | DET- GQE + PQE (N = 197) | P value | SET- GQE (N = 56) | DET- GQE + PQE (N = 56) | P value | |
Implantation n (%) | 16 (27.6) | 75 (19.0) | 0.129 | 14 (25.0) | 23 (20.5) | 0.510 |
OR (95%CI) | Reference | 0.675 (0.320—1.421) | 0.300 | Reference | 0.832 (0.372—1.858) | 0.653 |
Clinical Pregnancy n (%) | 15 (25.9) | 63 (32.0) | 0.374 | 13 (23.2) | 19 (33.9) | 0.209 |
OR (95%CI) | Reference | 1.350 (0.630—2.893) | 0.440 | Reference | 1.654 (0.712—3.839) | 0.242 |
Live birth n (%) | 12 (20.7) | 45 (22.8) | 0.729 | 11 (19.6) | 19 (33.9) | 0.088 |
OR (95%CI) | Reference | 1.175 (0.512—2.698) | 0.704 | Reference | 2.068 (0.867—4.933) | 0.102 |
Multiple birth n (%) | 1 (8.3) | 7 (15.6) | 0.863 | 1 (9.1) | 4 (21.1) | 0.626 |
OR (95%CI) | Reference | 7.666 (0.481—122.201) | 0.149 | Reference | 2.258 (0.212—24.020) | 0.500 |
Miscarriage n (%) | 3 (20.0) | 18 (28.6) | 0.727 | 2 (15.4) | 0 (0.0) | 0.157 |
OR (95%CI) | Reference | 1.100 (0.232—5.209) | 0.905 | - | - | - |
Preterm birth n (%) | 1 (8.3) | 7 (15.6) | 0.863 | 1 (9.1) | 5 (26.3) | 0.372 |
OR (95%CI) | Reference | 4.925 (0.034—704.376) | 0.529 | Reference | 3.102 (0.323—29.829) | 0.327 |
Gestational age (weeks) | 38.4 ± 2.4 | 38.4 ± 1.9 | 0.938 | 38.4 ± 2.5 | 37.7 ± 1.8 | 0.345 |
OR (95%CI) | Reference | 1.000 (0.372—2.687) | 0.999 | Reference | 0.582 (0.146—2.324) | 0.444 |
Birth height (mm) | 48.8 ± 1.6 | 48.9 ± 2.2 | 0.954 | 48.8 ± 1.7 | 48.0 ± 2.6 | 0.341 |
OR (95%CI) | Reference | 1.306 (0.464—3.674) | 0.613 | Reference | 0.685 (0.210—2.234) | 0.531 |
Birth weight (g) | 2993.5 ± 660.5 | 3074.6 ± 589.6 | 0.666 | 2993.8 ± 689.9 | 2754.8 ± 470.1 | 0.234 |
OR (95%CI) | Reference | 1.033 (0.926—1.152) | 0.566 | Reference | 0.936 (0.825—1.063) | 0.310 |
Low birth weight n (%) | 2 (15.4) | 6 (11.5) | 1.000 | 2 (16.7) | 5 (21.7) | 1.000 |
OR (95%CI) | - | - | - | Reference | 1.539 (0.134—17.640) | 0.729 |
Congenital anomalies n (%) | 0 | 0 | - | 0 | 0 | - |
OR (95%CI) | - | - | - | - | - | - |