Letrozole-stimulated endometrial preparation protocol is a superior alternative to hormone replacement treatment for frozen embryo transfer in women with polycystic ovary syndrome, a cohort study

Table 3 Crude and adjusted odds rations of pregnancy and obstetric outcomes of HRT and LS groups

Outcomes	cOR (95%CI)	aOR (95%CI)
Clinical pregnancy rate	1.35(1.17,1.55)	1.41(1.18,1.68) ^a
Miscarriage rate	0.68(0.56,0.84)	0.68(0.53,0.89) ^a
Early miscarriage rate	0.73(0.57,0.92)	0.69(0.51,0.94) ^a
Hypertensive disorders of pregnancy	0.73(0.53,1.01)	0.63(0.42,0.95) ^a
Gestational diabetes mellitus	0.77(0.62,0.96)	0.71(0.53,0.93) ^a
Live birth rate	1.45(1.27,1.65)	1.49(1.27,1.76) ^a
Preterm birth	0.99(0.82,1.19)	1.09(0.86,1.38)^b
Cesarean delivery	0.8(0.65,0.97)	0.78(0.60,1.01)^c
SGA
Singleton	1.87(1.14,3.07)	1.58(0.81,3.05)^b
Twin	1.02(0.51,2.05)	0.79(0.33,1.90)^b
LGA
Singleton	0.71(0.55,0.92)	0.81(0.58,1.13)^b
Twin	0.65(0.44,0.97)	0.62(0.38,1.00)^b

OR, odds ratio; CI, confidence interval. Odds ratios were obtained via a multiple logistic regression analysis. Significantly increased or reduced odds are indicated by boldface
a Adjusted for maternal age, maternal BMI, FSH, LH/FSH, AMH, AFC, P before embryo transfer, E2 before embryo transfer, endometrial thickness before transfer, number of embryos transferred, quality of embryos transferred, developmental stage of embryos transferred, IR and basic diseases of women
b Adjusted for maternal age, maternal BMI, FSH, LH/FSH, AMH, AFC, P before embryo transfer, E2 before embryo transfer, endometrial thickness before transfer, number of embryos transferred, quality of embryos transferred, developmental stage of embryos transferred, IR, basic diseases of women, HDP and GDM
c Adjusted for maternal age, maternal BMI, FSH, LH/FSH, AMH, AFC, P before embryo transfer, E2 before embryo transfer, endometrial thickness before transfer, number of embryos transferred, quality of embryos transferred, developmental stage of embryos transferred, IR, basic diseases of women, HDP, GDM and gestational age

ISSN: 1477-7827