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Table 1 Basic characteristics of HRT and LS groups

From: Letrozole-stimulated endometrial preparation protocol is a superior alternative to hormone replacement treatment for frozen embryo transfer in women with polycystic ovary syndrome, a cohort study

Characteristics

HRT group

(n = 1700)

LS group

(n = 2007)

P

Maternal age (years)

29.49 ± 3.58

29.86 ± 3.76

0.002

Maternal body mass index(kg/m2)

22.44 ± 2.91

22.27 ± 2.96

0.033

Infertility duration (years)

3.64 ± 2.44

3.61 ± 2.5

0.443

Gravidity

0.67 ± 1.03

0.68 ± 1.04

0.905

Parity

0.11 ± 0.34

0.12 ± 0.36

0.379

Cause of infertility

  

0.177

Male factor

453(29.53)

520(26.98)

 

Endometriosis

22(1.43)

25(1.30)

 

Uterine factor

258(16.82)

295(15.31)

 

Tubal factor

718(46.81)

982(50.96)

 

Unexplained infertility

83(5.41)

105(5.45)

 

FSH (IU/L)

5.28 ± 1.41

5.47 ± 1.47

< 0.001

LH (IU/L)

7.35 ± 6.02

7.19 ± 5.25

0.403

LH/FSH

1.41 ± 1.06

1.34 ± 0.95

0.009

Total T (ng/mL)

1.47 ± 6.46

2.41 ± 9.17

0.055

AMH (ng/mL)

12.46 ± 6.69

11.13 ± 6.73

< 0.001

AFC

47.48 ± 24.6

48.82 ± 23.44

0.007

Menstrual cycle (days)

57.98 ± 36.08

53.92 ± 28.06

0.144

P before embryo transfer(ng/ml)

8.64 ± 3.87

13.64 ± 6.99

< 0.001

E2 before embryo transfer(pg/ml)

448.97 ± 674.36

110.79 ± 184.88

< 0.001

Endometrial thickness before transfer(mm)

11.58 ± 1.7

11.49 ± 1.64

0.353

Number of embryos transferred

1.55 ± 0.5

1.58 ± 0.49

0.097

Quality of embryos transferred

  

0.198

Good quality

1124(66.12)

1367(68.11)

 

Non-good quality

576(33.88)

640(31.89)

 

Developmental stage of embryos transferred

  

0.010

Blastocyst (day 5)

1126(66.24)

1247(62.13)

 

Cleavage stage (day 3)

574(33.76)

760(37.87)

 

Phenotypes of metabolic disorder

   

IR

1355(79.71)

1694(84.4)

< 0.001

Elevation of fasting plasma glucose

212(15.33)

247(14.02)

0.301

Elevation of blood pressure

282(17)

320(16.14)

0.486

Central obesity

470(27.65)

509(25.36)

0.116

  1. Date were expressed as the mean ± standard deviation or number (%)
  2. Difference between the groups were analyzed by the Mann-Whitney U-test or chi-squared test