Table 3 The impact of embryo biopsy on anthropometrics from birth up to 2 years in frozen cycles

At birth

N=222

N=322

N=751

 Weight (g)

3418 (583)

3434 (537)

3402 (532)

16 [-65.9,97.8]

-51.2 [-136.6, 34.2]

32 [-38.3,101.6]

13.6 [-59.6,86.8]

 Weight SDS

0.17 (1.0)

0.14 (1.1)

0.11 (1.2)

0.06 [-0.09,0.21]

-0.05 [-0.20,0.12]

0.04 [-0.099,0.17]

0.03 [-0.12,0.17]

 Length (cm)

50.5 (2.8)

50.5 (2ss.6)

50.3 (2.5)

0.18 [-0.22,0.59]

-0.08 [-0.51,0.35]

0.22 [-0.12,0.55]

0.12 [-0.24,0.48]

 Length SDS

0.10 (1.3)

0.12 (1.3)

0.01 (1.2)

0.09 [-0.10,0.28]

-0.04 [-0.24,0.17]

0.11 [-0.047,0.28]

0.09 [-0.09,0.26]

 Head circumference (cm)

34.6 (2.0)

34.7 (1.9)

34.5 (1.8)

0.12 [-0.20,0.44]

-0.09 [-0.43,0.26]

0.21 [-0.072,0.49]

0.11 [-0.19,0.41]

 Head circumference SDS

0.02 (1.5)

0.08 (1.3)

-0.06 (1.4)

0.08 [-0.17,0.34]

-0.10 [-0.37,0.17]

0.15 [-0.070,0.36]

0.07 [-0.16,0.31]

At infancy

N=126

N=193

N=345

 Age (years)

0.4 (0.4)

0.5 (0.5)

0.5 (0.2)

 Weight SDS

0.16 (1.2)

0.05 (1.0)

0.16 (1.3)

0.01 [-0.25,0.26]

-0.02 [-0.30,0.26]

-0.10 [-0.31,0.11]

-0.17 [-0.40,0.06]

 Height SDS

0.19 (1.3)

0.09 (1.1)

0.23 (1.4)

-0.04 [-0.31,0.24]

0.03 [-0.27,0.33]

-0.14 [-0.37,0.084]

-0.20 [-0.45,0.05]

 Head circumference SDS

0.22 (1.1)

0.24 (0.9)

0.19 (1.1)

0.03 [-0.21,0.26]

0.01 [-0.25,0.26]

0.05 [-0.14,0.23]

-0.01 [-0.21,0.19]

At childhood

N=57

N=128

N=150

 Age (years)

2.3 (0.5)

2.2 (0.4)

2.2 (0.4)

 Weight SDS

-0.05 (0.8)

-0.03 (1.1)

-0.15 (1.0)

0.10 [-0.20,0.39]

0.18 [-0.16,0.52]

0.12 [-0.12,0.37]

0.03 [-0.25,0.31]

 Height SDS

0.10 (1.1)

-0.17 (1.1)

-0.17 (1.1)

0.27 [-0.067,0.60]

0.52 [0.15,0.89]

-0.002 [-0.26,0.25]

-0.05 [-0.33,0.24]

 Head circumference SDS

0.34 (1.1)

0.25 (0.9)

0.20 (1.0)

0.14 [-0.20,0.47]

0.11 [-0.27,0.48]

0.04 [-0.19,0.27]

0.02 [-0.25,0.29]

 Waist circumference SDS

0.90 (0.8)

0.98 (1.0)

0.61 (1.1)

0.29 [-0.10,0.67]

0.36 [-0.08,0.80]

0.37 [0.07,0.66]

0.35 [0.03,0.69]

 Mid-upper arm circumference SDS

0.27 (0.8)

0.46 (1.0)

0.19 (1.0)

0.08 [-0.27,0.10]

0.02 [-0.40,0.44]

0.27 [0.00,0.54]

0.28 [-0.03,0.59]

 ∆ weight SDS birth to infancy

0.21 (1.1)

0.09 (1.1)

0.18 (1.3)

0.03 [-0.23,0.28]

0.12 [-0.16,0.41]

-0.09 [-0.30,0.13]

-0.04 [-0.27,0.19]

 ∆ height SDS birth to infancy

-0.13 (1.0)

-0.03 (1.0)

-0.22 (1.2)

-0.04 [-0.30,0.21]

0.05 [-0.23,0.33]

-0.21 [-0.43,0.02]

-0.23 [-0.47,0.07]

 ∆ weight SDS infancy to early childhood

0.18 (1.2)

0.01 (1.2)

0.22 (1.2)

0.08 [-0.28,0.44]

0.15 [-0.26,0.56]

0.19 [-0.08,0.45]

0.13 [-0.18,0.43]

 ∆ height SDS infancy to early childhood

-0.07 (1.1)

-0.23 (0.9)

-0.40 (1.5)

0.32 [-0.13,0.78]

0.46 [-0.06,0.97]

0.17 [-0.14,0.48]

0.17 [-0.19,0.52]