Table 2 The impact of embryo biopsy on neonatal outcome in liveborn children
| Â | EBD5 FET N=222 | EBD3 FET N=322 | EBD3 FRESH N=308 | Non-biopsy FET N=751 | Non-biopsy FRESH N=781 | EBD5 FET vs Non-Biopsy FET | EBD3 FET vs Non-Biopsy FET | EBD3 FRESH vs Non-Biopsy FRESH |
|---|---|---|---|---|---|---|---|---|
| Â | Â | Â | Â | Â | Â | Adjusteda OR (95%CI) | Adjusteda OR (95%CI) | Adjusteda OR (95%CI) |
Male sex | 108 (48.6) | 158 (49.1) | 159 (51.6) | 373 (49.7) | 383 (49.0) | Â | Â | Â |
Gestational age (weeks) (mean, SD) | 39.0 (2.2) | 39.2 (1.6) | 38.9 (1.7) | 39.1 (1.8) | 38.9 (1.9) | Â | Â | Â |
Premature birth <37weeks | 15 (6.8) | 26 (8.1) | 23 (7.5) | 69 (9.2) | 57 (7.3) | 1.00 [0.53, 1.88] | 1.08 [0.65, 1.80] | 1.08 [0.61, 1.91] |
SGA <-1.28 SDS | 5 (2.3) | 7 (2.2) | 14 (4.5) | 21 (2.8) | 33 (4.2) | 1.16 [0.40, 3.40] | 0.94 [0.36, 2.41] | 1.44 [0.69, 3.00] |
LGA >+1.28 SDS | 8 (4.0) | 13 (4.4) | 8 (2.7) | 29 (4.1) | 10 (1.4) | 0.91 [0.29, 1.21] | 1.19 [0.57, 2.49] | 2.17 [0.71, 6.54] |
Low birth weight <2500g | 12 (5.4) | 14 (4.3) | 21 (6.8) | 42 (5.6) | 53 (6.8) | 1.02 [0.33,3.12] | 0.87 [0.44, 1.73] | 1.24 [0.70, 2.22] |
Macrosomia >4000g | 29 (13.1) | 51 (15.8) | 34 (11.0) | 82 (10.9) | 40 (5.1) | 1.01 [0.60, 1.72] | 1.42 [0.94, 2.15] | 2.31 [1.35, 3.97]* |
Major congenital malformations | 5/204 (2.5) | 13/301 (4.3) | 13/292 (4.5) | 23/687 (3.3) | 26/713 (3.6) | 0.93 [0.31, 2.80] | 1.91 [0.86, 4.23] | 1.22 [0.56, 2.65] |