| 1st trimester | 2nd trimester | 3rd trimester | delivery | P |
---|---|---|---|---|---|
Control (n = 129) |  |  |  |  |  |
FGlu (mmol/L) | 4.40 ± 0.25 | 4.34 ± 0.19 | 4.31 ± 0.21a | 4.34 ± 0.32 | 0.038 |
FIns (pmol/L) | 7.24 ± 5.07 | 10.55 ± 10.47a | 11.52 ± 9.37a | 8.67 ± 5.16c | < 0.001 |
HOMA-IR | 1.42 ± 1.01 | 2.04 ± 2.08a | 2.22 ± 1.90a | 1.69 ± 0.99c | < 0.001 |
TG (mmol/L) | 1.57 ± 0.47 | 2.65 ± 0.88a | 3.39 ± 1.19a, b | 3.66 ± 1.47a, b, c | < 0.001 |
TC (mmol/L) | 4.44 ± 0.56 | 5.64 ± 0.81a | 5.96 ± 0.86a, b | 5.85 ± 1.10a, b | < 0.001 |
HDL-C (mmol/L) | 1.77 ± 0.33 | 2.06 ± 0.42a | 1.99 ± 0.39a, b | 1.82 ± 0.39b, c | < 0.001 |
LDL-C (mmol/L) | 2.22 ± 0.58 | 3.06 ± 0.83a | 3.33 ± 0.94a, b | 3.18 ± 1.00a | < 0.001 |
AI | 1.59 ± 0.52 | 1.81 ± 0.52a | 2.07 ± 0.56a, b | 2.28 ± 0.59a, b, c | < 0.001 |
Apo A1 (g/L) | 2.13 ± 0.34 | 2.53 ± 0.52a | 2.45 ± 0.41a | 2.35 ± 0.51a. b | < 0.001 |
ApoB (g/L) | 0.74 ± 0.16 | 0.99 ± 0.20a | 1.11 ± 0.21a, b | 1.12 ± 0.27a, b | < 0.001 |
ApoB/apoA1 | 0.36 ± 0.11 | 0.41 ± 0.12a | 0.47 ± 0.13a, b | 0.49 ± 0.14a, b, c | < 0.001 |
ART (n = 64) |  |  |  |  |  |
FGlu (mmol/L) | 4.39 ± 0.21 | 4.33 ± 0.18 | 4.34 ± 0.20 | 4.56 ± 0.34*, a, b, c | < 0.001 |
FIns (pmol/L) | 7.13 ± 3.49 | 8.94 ± 4.65a | 10.88 ± 5.32a, b | 11.85 ± 10.89*, a, b | < 0.001 |
HOMA-IR | 1.39 ± 0.68 | 1.72 ± 0.88a | 2.09 ± 1.02a, b | 2.40 ± 2.20*, a, b | < 0.001 |
TG (mmol/L) | 1.72 ± 0.57* | 2.77 ± 0.94a | 3.64 ± 1.34a, b | 4.34 ± 2.05*, a, b, c | < 0.001 |
TC (mmol/L) | 4.66 ± 0.63* | 5.85 ± 0.86a | 6.12 ± 0.94a | 6.16 ± 1.15a | < 0.001 |
HDL-C (mmol/L) | 1.73 ± 0.35 | 2.06 ± 0.43a | 1.96 ± 0.39a, b | 1.83 ± 0.37b, c | < 0.001 |
LDL-C (mmol/L) | 2.45 ± 0.68* | 3.30 ± 0.80a | 3.50 ± 0.94a | 3.30 ± 0.96a | < 0.001 |
AI | 1.79 ± 0.63* | 1.93 ± 0.55 | 2.20 ± 0.60a, b | 2.42 ± 0.66a, b, c | < 0.001 |
Apo A1 (g/L) | 2.10 ± 0.37 | 2.55 ± 0.49a | 2.46 ± 0.49a | 2.30 ± 0.44a, b | < 0.001 |
ApoB (g/L) | 0.79 ± 0.17* | 1.03 ± 0.21a | 1.14 ± 0.26a, b | 1.17 ± 0.30a, b | < 0.001 |
ApoB/apoA1 | 0.39 ± 0.12* | 0.42 ± 0.12a | 0.49 ± 0.16a, b | 0.53 ± 0.16a, b | < 0.001 |