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Table 1 Clinical information of subjects in the study

From: Expression and significance of cathepsin C and cathepsin D during pregnancy and Preeclampsia

Variables

Nonpregnant

First trimester

Second trimester

Third trimester

Preeclampsia

P value

Age (years)

28.6 ± 2.92

28.85 ± 2.97

29 ± 2.95

28.9 ± 2.98

30.74 ± 3.51

0.002c

BMI (kg/m2)

21.7 ± 2.5

21.93 ± 2.51

24.55 ± 2.75a

27.16 ± 2.73b

29.76 ± 4.07

0.000c

Gestational week for serum collection (week)

-

8.81 ± 2.58

21.28 ± 3.72a

39.68 ± 0.94b

36.52 ± 2.78

0.000c

Gestational week of delivery(week)

-

-

-

39.82 ± 0.96

36.77 ± 2.42

0.000c

Primigravida

41/60

38/60

37/60

36/60

78/100

0.015c

Systolic blood pressure (mmHg)

115.1 ± 7.74

112.15 ± 7.90

112.20 ± 8.05

113.2 ± 7.88

157.22 ± 10.34

0.000c

Diastolic blood pressure (mmHg)

73.95 ± 3.48

73.4 ± 3.24

73.5 ± 3.24

72.05 ± 3.52

105.54 ± 8.0

0.000c

  1. BMI: body mass index
  2. Data are expressed as the mean ± SD
  3. a Second trimester compared with first trimester: P < 0.001; b third trimester compared with second trimester: P < 0.001;c preeclampsia compared with third trimester: P < 0.05