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Table 5 Comparison of the baseline demographic features and true natural cycle characteristics of patients with luteinized unruptured follicle (LUF) or follicular collapse

From: The true natural cycle frozen embryo transfer - impact of patient and follicular phase characteristics on serum progesterone levels one day prior to warmed blastocyst transfer

Characteristics

LUF

n = 25

Follicular collapse

n = 153

P*

Age, years

34.0 (30.5–37.50)

36.5 (32.0–40.0)

0.135

Body mass index, kg/m2

23.4 (22.0–26.1)

22.7 (20.9–25.8)

0.305

Antral follicle count on Day 2/3, n

16 (9.5–18.0)

14 (8–19.0)

0.539

Cause of infertility, n (%)

  

0.770

 Unexplained infertility

6 (24.0)

51 (33.3)

 

 Male factor

10 (40.0)

44 (28.8)

 

 Advanced maternal age and/or diminished ovarian reserve

5 (20.0)

43 (28.1)

 

 Tubal factor

1 (4.0)

5 (3.3)

 

 Endometriosis

2 (8.0)

4 (2.6)

 

 Monogenic disorders

1 (4.0)

6 (3.9)

 

Duration of infertility, months

24.0 (16.5–39.0)

28.5 (15.3–50.0)

0.889

Number of previous IVF cycles, median (minimum-maximum)

0 (0–3)

0 (0–8)

0.615

Previous childbirth, n (%)

7 (28.0)

28 (18.3)

0.280

Follicular phase length, day

11.0 (9.5–14.5)

13.0 (12.0–15.0)

0.052

Follicle diameter one day prior to ovulation, mm

20.1 (19.2–21.1)

19.2 (17.8–20.9)

0.004

Peak E2 level, pg/mL

284.0 (228.0–360.1)

324.5 (265.0–392.8)

0.022

Peak LH level, IU/L

39.2 (31.3–54.0)

47.7 (36.4–59.3)

0.246

Follicular phase peak P4 level, ng/mL

1.0 (0.9–1.4)

1.1 (0.9–1.4)

0.121

Endometrial thickness one day prior to ovulation, mm

10.9 (9.9–11.4)

10.1 (9.0–11.7)

0.084

Serum P4 concentration on FET-1, ng/mL

9.3 (5.5–15.4)

13.6 (10.3–17.3)

0.002

  1. Values are given as median (25th – 75th percentiles), or n (%)
  2. *The Mann-Whitney U test was employed to compare continuous variables, while the Chi-square test was used to compare proportions
  3. IVF: in-vitro fertilization, FET: Frozen embryo transfer