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Fig. 5 | Reproductive Biology and Endocrinology

Fig. 5

From: Autophagy, a critical element in the aging male reproductive disorders and prostate cancer: a therapeutic point of view

Fig. 5

Examples of the target signaling pathways that have been studied for the treatment of ED and/or PCa. ED: erectile dysfunction; PCa: prostate cancer; PI3K: phosphoinositide 3-kinase; TSC1/2: tuberous sclerosis proteins 1 and 2; GTP: guanosine-5’-triphosphate; Rheb: Ras homolog enriched in the brain; mTORC1: mammalian target of rapamycin complex 1; AMPK: AMP-activated protein kinase; FoxO3: forkhead box O-3; SKP2: S-phase kinase-associated protein 2; CARM1: Coactivator-associated arginine methyltransferase 1; TFEB: Transcription Factor EB

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Reproductive Biology and Endocrinology

ISSN: 1477-7827

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