Fig. 2From: Autophagy, a critical element in the aging male reproductive disorders and prostate cancer: a therapeutic point of viewProposed role of ATG7 in acrosome biogenesis. ATG7 is involved in acrosome biogenesis by regulating the transport of proacrosomal vesicles and/or fusion with the acrosome. Germ cell-specific knockout of this gene in mouse models could result in the failure of acrosome biogenesis, which corresponds to globozoospermia in humansBack to article page