Table 2 Baseline parameters and clinical outcomes of the paired patients
HBOT | Concurrent Control | p-value | |
|---|---|---|---|
Patients, n | 41 | 41 | |
Cycle Cancellation Rate, n (%) | 6 (14.6) | 4 (9.8) | 0.737 |
Age, y | 35.32 ± 4.98 | 35.24 ± 4.03 | 0.942 |
BMI, kg/m2 | 23.09 ± 6.99 | 22.00 ± 2.53 | 0.348 |
Baseline FSH, mIU/ml | 7.03 ± 3.45 | 6.26 ± 3.18 | 0.351 |
Baseline LH, mIU/ml | 6.02 ± 3.60 | 6.02 ± 5.04 | 0.995 |
AMH, ng/ml | 3.22 ± 2.77 | 3.48 ± 2.81 | 0.678 |
Infertility Duration, y | 3.80 [1.50, 6.50] | 4.00 [2.11, 7.00] | 0.422 |
Patients with a History of IUA, n (%) | 26 (63.4) | 25 (61.0) | 0.820 |
AFS Score | 7.54 ± 2.61 | 6.50 ± 3.41 | 0.212 |
Infertility type, n (%) | |||
Primary Infertility | 5 (12.2) | 9 (22.0) | 0.379 |
Secondary Infertility | 36 (87.8) | 32 (78.1) | |
Etiology of Infertility, n (%) | |||
Tubal | 20 (48.8) | 20 (48.8) | 0.343 |
DOR | 3 (7.3) | 3 (7.3) | |
Male factors | 2 (4.9) | 2 (4.9) | |
RSA/PGT | 14 (34.2) | 8 (19.5) | |
IUA | 2 (4.9) | 6 (14.6) | |
Others | 0 (0) | 2 (4.9) | |
Average HBOT treatments, n | 28.48 ± 15.24 | - | - |
Endometrial Preparation Method, n (%) | 0.316 | ||
NC-FET | 8 (19.5) | 14 (34.1) | |
HRT-FET | 26 (63.4) | 22 (53.7) | |
GnRH-a FET | 7 (17.1) | 5 (12.2) | |
Initial ET, mm | 4.20 ± 1.24 | 4.48 ± 1.07 | 0.356 |
Duration of Estrogen Administration, day | 12.50 [12.00, 15.00] | 16.00 [14.50, 17.00] | < 0.001 |
ET on Endometrium Transformation Day, mm | 6.70 ± 1.21 | 6.59 ± 1.57 | 0.712 |
P levels on Day of Progesterone Administration, ng/ml | 0.30 ± 0.41 | 0.32 ± 0.38 | 0.893 |
Endometrial Pattern on Endometrium Transformation Day a, n (%) | |||
A | 1 (2.4) | 2 (4.9) | 0.392 |
B | 26 (63.4) | 20 (48.8) | |
C | 14 (34.2) | 19 (46.3) | |
ET on Embryo Transfer Day, mm | 6.75 ± 1.26 | 6.05 ± 1.06 | 0.456 |
Num. of Embryo Transferred | 1.20 ± 0.41 | 1.46 ± 0.51 | 0.019 |
Num. of Good-Quality Embryos Transferred | 0.69 ± 0.68 | 1.03 ± 0.76 | 0.049 |
Embryo Implantation Rate, n (%) | 14 (33.3) | 6 (11.1) | 0.008 |
Num. of Patients Received D3 Embryos, n | 9 | 15 | |
Intrauterine Pregnancy Rate, n (%) | 0 (0) | 1 (6.7) | 1 |
Biochemical Pregnancy Rate, n (%) | 1 (11.1) | 3 (20.0) | 1 |
Miscarriage, n (%) | - | 0 (0) | - |
Num. of Patients Received D5 Embryos | 26 | 22 | |
Intrauterine Pregnancy Rate, n (%) | 14 (53.8) | 4 (18.2) | 0.017 |
Biochemical Pregnancy Rate, n (%) | 2 (7.7) | 3 (13.6) | 0.649 |
Miscarriage, n (%) | 0 (0) | 1 (25) | 0.222 |