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Table 2 Follicular count (Ovarian reserves) of Control and Aspartame treated mice after 30 and 60 days

From: The impact of non-caloric artificial sweetener aspartame on female reproductive system in mice model

Follicle Count

Groups

Duration

30 days

60 days

Primordial follicles

Control

15.8 ± 2.59

16 ± 2.24

ASP

11.8 ± 1.92*

8.4 ± 1.14**

Primary follicles

Control

4 ± 1.58

4.4 ± 1.14

ASP

2 ± 1.0*

1.4 ± 0.55**

Secondary follicles

Control

5.2 ± 1.79

5.4 ± 1.82

ASP

2.4 ± 1.14**

1.8 ± 0.84**

Graffian follicles

Control

1.8 ± 0.84

2.2 ± 0.84

ASP

0.6 ± 0.55*

0.4 ± 0.55**

Atretic follicles

Control

1.4 ± 0.55

1.6 ± 0.55

ASP

5.2 ± 1.48*

9.4 ± 2.7**

  1. ± SD of six animals
  2. *Significant difference (p ≤ 0.05) compared to control by one way ANOVA
  3. **More significant difference (p ≤ 0.01) compared to control by one way ANOVA
  4. ***Highly significant difference (p ≤ 0.001) compared to control by one way ANOVA
  5. NS Non significant compared to control by one way ANOVA