Table 1 Body weight (g), relative organ weight (g/100 g b. w.), and GSI (mg/100 g b. w.) of control and aspartame (ASP) treated female mice after 30 and 60 days

Groups

Initial body weight

Final body weight

Percent weight gain

Control

20.00 ± 2.00

25.50 ± 1.05

27.5%

ASP-30

20.33 ± 2.06

19.83 ± 1.17^**

-2.46%

ASP-60

20.17 ± 2.79

21.33 ± 1.21^**

5.75%

Relative organ weight (g/100 g b. w.)

Duration

(days of treatment)

Groups

Control

ASP

Liver

30

4.77 ± 0.12

3.76 ± 0.28**

60

4.95 ± 0.69

3.12 ± 0.04**

Kidney

30

0.59 ± 0.03

0.39 ± 0.04**

60

0.60 ± 0.03

0.36 ± 0.05**

Gonadosomatic indices (GSI)

Duration

(days of treatment)

Groups

Control

ASP

30

39.3 ± 3.22

26.69 ± 2.86^**

60

48.33 ± 5.66

26.35 ± 4.93^**