Fig. 7

High TFPI2 expression in PE tissues and its effects on trophoblast cells. A The TFPI2 expression in placental tissues was tested by the qPCR and normalized to the GAPDH. The results showed that the DUXAP8 expression of 33 PE tissues is lower than the normal tissues. The TFPI2 relative expression in PE placental samples was compared with the normal tissues. B The western blot analysis of the expression of TFPI2 in the PE placental and normotensive placental tissues. C The Pearson correlation coefficient was conducted to analyze the correlation between the DUXAP8 and TFPI2 expression, r = -0.88. D The TFPI2 low expression affected cell viability for the si-DUXAP8-transfected trophoblasts. E The si-TFPI2 transfection reversed the cells migration transfected with the si-DUXAP8. Data results were expressed as mean ± SEM, *P < 0.05, **P < 0.01