Can biomarkers identified from the uterine fluid transcriptome be used to establish a noninvasive endometrial receptivity prediction tool? A proof-of-concept study

Table 2 WGCNA analysis of DEGs from uterine fluid

Module	Number of genes	Hub gene	Module-receptivity relationships	DAVID cluster	*p-value	Enrichment score
ME turquoise	510	ECI2	−0.7	GO:0016575 ~ histone deacetylation	0.0479	3.44
				GO:0004407 ~ histone deacetylase activity	0.0371
				GO:0016581 ~ NuRD complex	0.0416
ME blue	265	CXCL16	0.55	GO:0051056 ~ regulation of small GTPase mediated signal transduction	0.0192	3.5
				GO:0043547 ~ positive regulation of GTPase activity	0.0385
				GO:0005096 ~ GTPase activator activity	0.0557
ME yellow	78	ATP6V1B2	0.69	GO:0042470 ~ melanosome	0.0133	2.4
				GO:0045121 ~ membrane raft	0.0935
				GO:0005913 ~ cell-cell adherens junction	0.0935

ISSN: 1477-7827