Conditions | Metabolic parameter | Calculated parameter | Controls (n = 8) | PCOSr (n = 8) | p |
---|---|---|---|---|---|
OGTT | Insulin sensitivity | ISIMatsuda | 3.6 (2.4–7.3) | 3.8 (2.6–6.0) | 0.798 |
Insulin secretion | CIR30 | 1.1 (0.6–1.3) | 1.2 (0.8–1.7) | 0.574 | |
β-cell function | DIOGTT | 2.7 (2.3–4.7) | 4.4 (4.1–6.1) | 0.195 | |
NEFA suppressibility | Logn-linear slope | −0.028 (−0.030 – −0.018) | −0.040 (−0.044 – −0.036) | <0.001 | |
Logn-linear slope / AUCinsulin | −0.58 (−1.02 – −0.23) | −0.81 (−1.29 – −0.51) | 0.195 | ||
T50NEFA (min) | 40.6 (28.3–48.5) | 34.1 (24.4–47.0) | 0.645 | ||
FSivGTT | Insulin sensitivity | ISFSivGTT | 3.4 (1.8–3.6) | 3.2 (2.2–5.3) | 0.878 |
Insulin secretion | AIRg | 790 (343–813) | 496 (361–997) | 0.959 | |
β-cell function | DIFSivGTT | 1380 (1122–2563) | 1926 (1376–2264) | 0.442 | |
NEFA suppressibility | Logn-linear slope | −0.032 (−0.040 – −0.024) | −0.032 (−0.088 – −0.018) | 0.878 | |
Logn-linear slope / AUCinsulin | −4.33 (−6.42 – −3.14) | −3.33 (−7.64 – −2.67) | 0.505 | ||
T50NEFA (min) | 20.8 (16.2–26.9) | 18.1 (16.1–23.9) | 0.574 |