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Table 1 Effect of DDT treatment on glutathione-dependent enzymes and reducing power in testis of adult rat

From: p,p’-DDT induces testicular oxidative stress-induced apoptosis in adult rats

Parameters

Control

DDT 50 mg/kg

DDT 100 mg/kg

Gpx (U/mg Pt)

76.83 ± 1.99

58.26 ± 2.25a

29.6 ± 1b

GR (U/mg Pt)

42.37 ± 2.02

22.5 ± 1.76a

16.71 ± 0.78b

GST (U/mg Pt)

107.45 ± 2.82

109.86 ± 4.71

58.75 ± 3.29a

GSH (nmol/mg Pt)

59.36 ± 2.87

44.81 ± 1.53a

28.18 ± 2.63b

GSSG (nmol/mg Pt)

5.59 ± 0.21

7.25 ± 0.32a

9.98 ± 0.3b

GSSG/GSH (%)

0.089 ± 0.003

0.178 ± 0.004a

0.376 ± 0.036b

  1. Each value is the mean of 8 determinations with standard error (SEM). DDT treatment was preformed as described in Methods. a, b : p < 0.05 compared with controls (Tukey’s multiple comparison post hoc test)