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Fig. 3 | Reproductive Biology and Endocrinology

Fig. 3

From: Chronic effects of an anti-angiogenic thrombospondin-1 mimetic peptide, ABT-898, on female mouse reproductive outcomes

Fig. 3

CD31 and vimentin immunohistochemistry of ABT-898 treated and 5 % dextrose control uteri and ovaries. Semi-quantitative analysis of CD31+ blood vessels in the endometrium found no significant difference (p = 0.45, i) between ABT-898 (a) and 5 % dextrose (b) groups. Immunohistochemistry for CD31 also found that blood vessel development around antral follicles was not altered by ABT-898 (c, f, d, g), and semi-quantitative analysis found no significant difference (p = 0.75). Vimentin immunohistochemistry showed no difference in structure or number of microvessels (green arrows) between ABT-898 (e) and 5 % dextrose (h) corpus luteum. Scale bars represent 75 μm. FOV: Field of view

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