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Table 2 Family history of osteoporosis (FHO) and of hip fracture (FHF) regarding ESR1 and ESR2 genotypes.

From: Age-specific effects of estrogen receptors' polymorphisms on the bone traits in healthy fertile women: the BONTURNO study

 

FHO

FHF

FHO-FHF

FHO

FHF

FHO-FHF

 

positive

negative

ESR1 rs2234693

      

CC (n [%])

39 (17.6)

18 (17.6)

9 (14.7)

77 (24.0)

98 (22.1)

68 (24.1)

CT (n [%])

118 (53.1)

50 (49.1)

32 (52.5)

158 (49.0)

227 (51.2)

141 (50.0)

TT (n [%])

65 (29.3)

34 (33.3)

20 (32.8)

87 (27.0)

118 (26.7)

73 (25.9)

Total

222

102

61

322

443

282

ESR2 rs4986938

      

AA (n [%])

36 (16.3)

18 (18.2)

12 (19.7)

50 (15.8)

68 (15.5)

44 (15.8)

AG (n [%])

104 (47.1)

59 (59.6)

38 (62.3)

119 (37.5)

193 (44.0)

127 (45.5)

GG (n [%])

81 (36.6)

22 (22.2)

11 (18.0)

148 (46.7)

178 (40.5)

108 (38.7)

Total

221

99

61

317

439

279