Figure 6
Effects of THG113.31 on spontaneous myometrial contractions. A Representative recordings of spontaneous contractions of pregnant human myometrium under control conditions and (B) the effects of cumulative additions of THG113.31 (1 nM, 10 nM, 100 nM, 1 μM and 10 μM) at 20 min intervals are shown. (C & D) The uterorelaxant effect was significantly attenuated by pre-incubation with the BKCa channel antagonist, IbTX