Figure 2From: Increase of mitochondrial DNA content and transcripts in early bovine embryogenesis associated with upregulation of mtTFA and NRF1 transcription factorsComparison of COX1, mtTFA and NRF1 transcript levels in oocytes and at various stages of bovine embryonic development. Levels of COX1 mRNA remain constant from the oocyte to the 8/16-cell stage, and then increase sharply from the morula stage onwards (p = 0.002). mtTFA mRNA was not detected before the morula stage. The abundance of this transcript increased dramatically at the blastocyst stage (p < 0.0001). The abundance of NRF1 transcripts remained practically constant from the oocyte to the morula stage, after which it increased significantly up to the blastocyst stage (p < 0.0001).Back to article page