Figure 4From: Mitochondrial 3 beta-hydroxysteroid dehydrogenase (HSD) is essential for the synthesis of progesterone by corpora lutea: An hypothesisRepresentative diagram of the proposed effect of the concurrent synthesis of HSD and cytochrome P450 scc on the intracellular distribution of HSD in luteal cells. Initiated by LH; the transcription of HSD mRNA and P450scc mRNA results in the simultaneous production of HSD and P450scc. The two enzymes bind to each other to form a complex, which is then inserted into the inner mitochondrial membrane. Molecules of HSD that do not bind to P450scc are inserted into the membrane of the endoplasmic reticulum.Back to article page