Table 2 Human studies on follicle size and IVF outcomes
Study design | Age | COH | IVF/ICSI | Oocytes | Size mm | % MII | % fert | % cleavage | % good quality embryo | |
|---|---|---|---|---|---|---|---|---|---|---|
Wittmack 1994 [13] | R | 23-49 | Long | Only IVF | 6879 | 12-15-18-20-21-23-24 | Worst recovery rate under 12 mm and over 24 mm | Increasing from 12 mm onwards | Increasing from 12 mm onwards | None |
Inaudi 1995 [24] | R | 28-37 | Short | Only IVF | 179 | 16-22 | None in the recovery rate | n.e. | n.e. | n.e. |
Dubey 1995 [26] | R | n.e. | Long | Only IVF | 2429 | 14-16-22 | n.e. | Increasing from 16 mm onwards | n.e. | n.e. |
Ectors 1997 [17] | P | n.e. | Short | IVF/ICSI | 2324 | 16-23 | IVF: n.e. | IVF: increasing from 16 to 23 mm, later decreasing | IVF: increasing from 16 to 23 mm, later decreasing | IVF: increasing from 16 to 23 mm, later decreasing |
ICSI: increasing from 16 mm onwards | ICSI: none | ICSI: none | ICSI: increasing from 16 mm onwards | |||||||
Bergh 1998 [18] | P | 33.0 | Long | IVF/ICSI | 4159 | 16 | n.e. | IVF: increasing | IVF: none | n.e. but increasing pregnancy rate only in IVF |
ICSI: none | ICSI: none | |||||||||
Teisser 2000 [22] | P | 28.0 | Long | Only IVF | 150 | 14 | Increasing | n.e. | Increasing | n.e. |
Triwitayakorn 2003 [14] | P | 35.9 | Long short | Only ICSI | 991 | 10-14 | Always increasing together with oocyte recovery rate | None | n.e. | none |
Rosen 2008 [19] | P | 34.1 | Long shortantag | IVF/ICSI | 2934 | 10-13-16-19 | IVF: n.e. | IVF: always increasing | n.e. | IVF: always increasing |
ICSI: always increasing | ICSI: always increasing | ICSI: always increasing | ||||||||
Lee 2010 [23] | P | 33.5 | Long | Only ICSI | 819 | 18-20 | Increasing from 18 mm onwards | None | None | none |
Mehri 2013 [20] | P | n.e. | Long | IVF/ICSI | 360 | 15-18 | Increasing from 18 mm onwards | Increasing from 18 mm onwards | None | none |