Species | Placentation characteristics | Depth of Invasion | Molecule produce; # oligosaccharides (oligos); pI of dimer; circulating 1/2-life; relative biopotency | Brain mass(% body weight) | First appearance (million years ago) |
---|---|---|---|---|---|
Humans | Hemochorial | 1/3 rd myometrium | CG; 8 oligos; pI 3.5; 1/2-life 36 h, 109X | 2.4% | 0.1 |
Advanced simian primates | Hemochorial | 1/10th myometrium | CG; 6 oligos; pI 4.9; 1/2-life 6 h; 18X | 0.74% | 20 |
Early simian primates | Hemochorial | through decidua | CG; 5 oligos; pI 6.3; 1/2-life 2.4 h; 7.3X | 0.17% | 37 |
Prosimian primate | Epitheliochorial | non-implanting | LH; 3 oligos; pI 9.0; 1/2-life 0.33 h; 1X | 0.07% | 55 |