From: Ovarian surface epithelium: family history and early events in ovarian cancer
 | NFH-OSE | FH-OSE |
---|---|---|
Response to environmental signals | greater | lesser |
Growth potential | greater | lesser |
Telomeric length | longer | shorter |
Metaplastic colonies in primary culture | rare | frequent |
Expression of | Â | Â |
   CA125 | rare | prominent |
   E-cadherin | rare | prominent |
   High molecular weight keratin | less | more |
   Collagen III | more | less |
Coexpression of HGF and Met receptor | rare | frequent |
Signaling pathways (such as PI3K) | non-activated | activated |