Table 2 Effect of p-nonylphenol (NP; 50 μg and 500 μg) and resveratrol (RES; 3 mg) on different body parameters in female outbred CD1 mice. The control and experimental groups of the same sex were killed at identical times. The body weights and organ weights were taken individually. The ratio between the organ weight and body weight represents the relative organ weight. (* P < 0.05, ** P < 0.01).
| Â | P | F1 | ||||||
|---|---|---|---|---|---|---|---|---|
Varible | Control | NP 50 | NP 500 | RES | Control | NP 50 | NP 500 | RES |
Body weight (g) | 37.34 ± 0.70 | 33.54 ± 0.47** | 35.68 ± 0.62 | 35.05 ± 1.02 | 35.90 ± 1.84 | 33.94 ± 1.66 | 38.29 ± 0.90 | 35.72 ± 1.42 |
Ovary weight (mg) | 13.60 ± 0.89 | 13.50 ± 0.60 | 12.91 ± 0.73 | 10.12 ± 0.57* | 14.37 ± 0.68 | 13.84 ± 0.94 | 15.49 ± 0.85 | 13.89 ± 1.58 |
Ovary weight/Body weight | 0.37 ± 0.03 | 0.40 ± 0.02 | 0.36 ± 0.02 | 0.29 ± 0.03* | 0.40 ± 0.01 | 0.42 ± 0.03 | 0.40 ± 0.02 | 0.39 ± 0.05 |
Liver weight (mg) | 2613 ± 752 | 2532 ± 691 | 2554 ± 35 | 2642 ± 83 | 2857 ± 143 | 2799 ± 162 | 2945 ± 907 | 2361 ± 127 |
Liver weight/Body weight | 69.98 ± 20.14 | 75.49 ± 20.60 | 71.58 ± 0.98 | 77.59 ± 2.44 | 79.58 ± 3.98 | 82.47 ± 4.77 | 76.91 ± 23.53 | 66.10 ± 3.56 |
Kidney weight (mg) | 292.7 ± 7.3 | 249.6 ± 4.5 | 250.4 ± 5.4 | 306.9 ± 10.3 | 291.8 ± 9.0 | 283.4 ± 9.3 | 287.1 ± 9.6 | 283.0 ± 21.0 |
Kidney weight/Body weight | 7.80 ± 0.20 | 7.46 ± 0.20** | 7.01 ± 0.06* | 8.40 ± 0.54 | 8.17 ± 0.24 | 8.59 ± 0.24 | 7.44 ± 0.23 | 7.90 ± 0.36 |
Spleen weight (mg) | 159.9 ± 14.2 | 139.2 ± 3.0 | 156.6 ± 9.1 | 134.4 ± 10.8 | 174.1 ± 18.6 | 163.0 ± 21.8 | 170.9 ± 4.2 | 149.1 ± 22.0 |
Spleen weight/Body weight | 4.36 ± 0.33 | 4.10 ± 0.22 | 4.39 ± 0.25 | 3.76 ± 0.38 | 4.79 ± 0.29 | 4.85 ± 0.49 | 4.46 ± 0.09 | 4.20 ± 0.64 |