https://rbej.biomedcentral.com/articles/10.1186/s12958-017-0230-0
https://rbej.biomedcentral.com/articles/10.1186/s12958-017-0231-z
https://rbej.biomedcentral.com/articles/10.1186/s12958-017-0228-7
https://rbej.biomedcentral.com/articles/10.1186/s12958-017-0229-6