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  1. Human Plexin-B1 is expressed in two truncated forms. The long form encodes a trans-membranal protein, while the short form, which is bound to the cell surface and partially secreted, possibly serves as a decoy...

    Authors: Avital Regev, Shlomit Goldman and Eliezer Shalev
    Citation: Reproductive Biology and Endocrinology 2007 5:12
    Content type: Research Published on:

  2. The prostate is a sexual gland that produces important substances for the potency of sperm to fertilize eggs within the female reproductive tract, and is under complex endocrine control. Taking advantage of th...

    Authors: Maria Elena Hernandez, Abraham Soto-Cid, Gonzalo E Aranda-Abreu, Rosaura Díaz, Fausto Rojas, Luis I Garcia, Rebeca Toledo and Jorge Manzo
    Citation: Reproductive Biology and Endocrinology 2007 5:11
    Content type: Research Published on:

  3. PGF2alpha exerts a significant contractile effect on myometrium and is central to human labour. THG113.31, a specific non-competitive PGF2alpha receptor (FP) antagonist, exerts an inhibitory effect on myometri...

    Authors: Helen C Doheny, Michael J O'Reilly, Donal J Sexton and John J Morrison
    Citation: Reproductive Biology and Endocrinology 2007 5:10
    Content type: Research Published on:

  4. The current study was designed to compare antral follicle count (AFC) and basal ovarian volume (BOV), the exogenous FSH ovarian reserve test (EFORT) and the clomiphene citrate challenge test (CCCT), with respe...

    Authors: Janet Kwee, Mariet E Elting, Roel Schats, Joseph McDonnell and Cornelis B Lambalk
    Citation: Reproductive Biology and Endocrinology 2007 5:9
    Content type: Research Published on:

  5. Hypospadias is a common inborn error of the male urethral development, for which the aetiology is still elusive. Polymorphic variants in genes involved in the masculinisation of male genitalia, such as the and...

    Authors: Ana Beleza-Meireles, Michela Barbaro, Anna Wedell, Virpi Töhönen and Agneta Nordenskjöld
    Citation: Reproductive Biology and Endocrinology 2007 5:8
    Content type: Research Published on:

  6. Paradoxical sleep deprivation (PSD) associated with cocaine has been shown to enhance genital reflexes (penile erection-PE and ejaculation-EJ) in Wistar rats. Since hypertension predisposes males to erectile d...

    Authors: Monica L Andersen, Raquel CS Martins, Tathiana AF Alvarenga, Isabela B Antunes, Ligia A Papale and Sergio Tufik
    Citation: Reproductive Biology and Endocrinology 2007 5:7
    Content type: Research Published on:

  7. The trophoblast, i.e. the peripheral part of the human conceptus, exerts a crucial role in implantation and placentation. Both processes properly occur as a consequence of an intimate dialogue between fetal an...

    Authors: Laura Lunghi, Maria E Ferretti, Silvia Medici, Carla Biondi and Fortunato Vesce
    Citation: Reproductive Biology and Endocrinology 2007 5:6
    Content type: Review Published on:

  8. Bovine luteal parenchymal cells express class II major histocompatibility complex (MHC) molecules and stimulate class II MHC-dependent activation of T cells in vitro. The ability of a class II MHC-expressing c...

    Authors: Matthew J Cannon, John S Davis and Joy L Pate
    Citation: Reproductive Biology and Endocrinology 2007 5:5
    Content type: Research Published on:

  9. Embryo implantation plays a major role in embryogenesis and the outcome of pregnancy. Plasminogen activators (PAs) have been implicated in mammalian fertilization, early stages of development and embryo implan...

    Authors: Eliahu D Aflalo, Uriel A Sod-Moriah, Gad Potashnik and Iris Har-Vardi
    Citation: Reproductive Biology and Endocrinology 2007 5:4
    Content type: Research Published on:

  10. Cervical ripening resembles an inflammatory reaction. Estrogens induce leukocyte migration into tissue and factors promoting cervical remodeling and labor, although the mechanisms are only partially known. The...

    Authors: Hong Wang and Ylva Vladic Stjernholm
    Citation: Reproductive Biology and Endocrinology 2007 5:3
    Content type: Research Published on:

  11. In IVF-ICSI cycles with single embryo transfer (SET), embryo selection for transfer is of crucial importance. The present study aimed to define which embryo parameters might be related to the implantation pote...

    Authors: Tiziana della Ragione, Greta Verheyen, Evangelos G Papanikolaou, Lisbet Van Landuyt, Paul Devroey and Andre Van Steirteghem
    Citation: Reproductive Biology and Endocrinology 2007 5:2
    Content type: Research Published on:

  12. A major event in the post-meiotic development of male germ cells is the formation of the acrosome. This process can be perturbed in C57BL/6 mice by administration of the small molecule miglustat (N-butyldeoxyn...

    Authors: Wilhelm Bone, Charlotte M Walden, Martin Fritsch, Ulrike Voigtmann, Eckhard Leifke, Ulrich Gottwald, Stephanie Boomkamp, Frances M Platt and Aarnoud C van der Spoel
    Citation: Reproductive Biology and Endocrinology 2007 5:1
    Content type: Research Published on:

  13. ICI 182,780 (ICI) belongs to a new class of antiestrogens developed to be pure estrogen antagonists and, in addition to its therapeutic use, it has been used to knock-out estrogen and estrogen receptor (ER) ac...

    Authors: Patrícia IS Pinto, Pratap B Singh, João B Condeça, Helena R Teodósio, Deborah M Power and Adelino VM Canário
    Citation: Reproductive Biology and Endocrinology 2006 4:67
    Content type: Research Published on:

  14. Although the control of ovarian production of steroid hormones is mainly of endocrine nature, there is increasing evidence that the nervous system also influences ovarian steroidogenic output. The purpose of t...

    Authors: Marilina Casais, Silvia M Delgado, Zulema Sosa, Carlos M Telleria and Ana M Rastrilla
    Citation: Reproductive Biology and Endocrinology 2006 4:66
    Content type: Research Published on:

  15. Delayed uterine involution has negative effects on the fertility of cows; use of prostaglandin F2alpha alone as a single treatment has not been shown to consistently improve fertility. Combined administration ...

    Authors: Gaby Hirsbrunner, Heinz W Burkhardt and Adrian Steiner
    Citation: Reproductive Biology and Endocrinology 2006 4:65
    Content type: Research Published on:

  16. The orphan nuclear receptor NR5A1 (steroidogenic factor-1, SF-1) is a master regulator of tissue-specific gene expression in reproductive and steroidogenic tissues. Two activating functions, AF-1 and AF-2, hav...

    Authors: Norbert Walther, Martina Jansen, Wasima Akbary and Richard Ivell
    Citation: Reproductive Biology and Endocrinology 2006 4:64
    Content type: Research Published on:

  17. The E2F family of transcription factors is required for the activation or repression of differentially expressed gene programs during the cell cycle in normal and abnormal development of tissues. We previously...

    Authors: Kame S El-Darwish, Martti Parvinen and Jorma Toppari
    Citation: Reproductive Biology and Endocrinology 2006 4:63
    Content type: Research Published on:

  18. The mycotoxin zearalenone (ZEA) and its derivatives, alpha and beta-zearalenol (alpha and beta-ZOL), synthesized by genera Fusarium, often occur as contaminants in cereal grains and animal feeds. The importanc...

    Authors: Fiorenza Minervini, Alessandra Giannoccaro, Francesca Fornelli, Maria Elena Dell'Aquila, Paolo Minoia and Angelo Visconti
    Citation: Reproductive Biology and Endocrinology 2006 4:62
    Content type: Research Published on:

  19. In the mouse, embryo culture results in a characteristic phenotype of retarded embryo preimplantation development and reduced numbers of cells within embryos. The expression of TRP53 is central to the regulati...

    Authors: Vashe Chandrakanthan, Aiqing Li, Omar Chami and Christopher O'Neill
    Citation: Reproductive Biology and Endocrinology 2006 4:61
    Content type: Research Published on:

  20. Total and intra-mitochondrial gonadal cholesterol concentrations are decreased in fish exposed to the phytoestrogen beta-sitosterol (beta-sit). The present study examined the potential for beta-sit to disrupt ...

    Authors: Rainie L Sharpe, Melissa Drolet and Deborah L MacLatchy
    Citation: Reproductive Biology and Endocrinology 2006 4:60
    Content type: Research Published on:

  21. Determining sexual fate is an integral part of reproduction, used as a means to enrich the genome. A variety of such regulatory mechanisms have been described so far and some of the more extensively studied on...

    Authors: Panagiota Manolakou, Giagkos Lavranos and Roxani Angelopoulou
    Citation: Reproductive Biology and Endocrinology 2006 4:59
    Content type: Review Published on:

  22. The aim of our research was to examine the ability of density gradient preparation BoviPure® and swim up method on bull sperm separation and in vitro embryo production (IVP) systems. Frozen/thawed semen from six ...

    Authors: Marko Samardzija, Martina Karadjole, Iva Getz, Zdenko Makek, Marijan Cergolj and Tomislav Dobranic
    Citation: Reproductive Biology and Endocrinology 2006 4:58
    Content type: Research Published on:

  23. Angiogenesis is a crucial process in follicular development and luteogenesis. The nerve growth factor (NGF) promotes angiogenesis in various tissues. An impaired production of this neurotrophin has been associ...

    Authors: Marcela Julio-Pieper, Hernán E Lara, Javier A Bravo and Carmen Romero
    Citation: Reproductive Biology and Endocrinology 2006 4:57
    Content type: Research Published on:

  25. In the mouse, culture of embryonic stem (ES) cells may decrease their pluripotency and give rise to foetal abnormalities in recipient embryos. These abnormalities are frequently associated with both, chromosom...

    Authors: Miguel A Ramírez, Eva Pericuesta, Raul Fernandez-Gonzalez, Pedro Moreira, Belen Pintado and Alfonso Gutierrez-Adan
    Citation: Reproductive Biology and Endocrinology 2006 4:55
    Content type: Research Published on:

  26. Recent work has shown that glucose may induce cell injury through the action of free radicals generated by autooxidation or through hypoxanthine phosphoribosyltransferase inhibition. The effect of glucose duri...

    Authors: Ni Wayan Kurniani Karja, Kazuhiro Kikuchi, Mokhamad Fahrudin, Manabu Ozawa, Tamás Somfai, Katsuhiko Ohnuma, Junko Noguchi, Hiroyuki Kaneko and Takashi Nagai
    Citation: Reproductive Biology and Endocrinology 2006 4:54
    Content type: Research Published on:

  27. The corpus luteum is an endocrine gland whose limited lifespan is hormonally programmed. This debate article summarizes findings of our research group that challenge the principle that the end of function of t...

    Authors: Carlos M Telleria
    Citation: Reproductive Biology and Endocrinology 2006 4:53
    Content type: Debate Published on:

  28. Activins stimulate pituitary FSH synthesis via transcriptional regulation of the FSHbeta subunit gene (Fshb). Like other members of the TGFbeta superfamily, these ligands signal through complexes of type I and...

    Authors: Daniel J Bernard, Katharine B Lee and Michelle M Santos
    Citation: Reproductive Biology and Endocrinology 2006 4:52
    Content type: Research Published on:

  29. Pregnancy in mammals featuring hemochorial placentation introduces a major conflict with the mother's immune system, which is dedicated to repelling invaders bearing foreign DNA and RNA. Numerous and highly so...

    Authors: Joan S Hunt, Daudi K Langat, Ramsey H McIntire and Pedro J Morales
    Citation: Reproductive Biology and Endocrinology 2006 4(Suppl 1):S10
    Content type: Review Published on:

    This article is part of a Supplement: Volume 4 Supplement 1

  30. Endometriosis is a disorder that affects 5% of the normal population but is present in up to 40% of women with pelvic pain and/or infertility. Recent evidence suggests that the endometrium of women with endome...

    Authors: Bruce A Lessey, Wilder A Palomino, KBC Apparao, Steven L Young and Ruth A Lininger
    Citation: Reproductive Biology and Endocrinology 2006 4(Suppl 1):S9
    Content type: Research Published on:

    This article is part of a Supplement: Volume 4 Supplement 1

  31. Selective progesterone receptor modulators (SPRMs) represent a new class of progesterone receptor ligands that exert clinically relevant tissue-selective progesterone agonist, antagonist, partial, or mixed ago...

    Authors: Kristof Chwalisz, Ramesh Garg, Robert Brenner, Ov Slayden, Craig Winkel and Walter Elger
    Citation: Reproductive Biology and Endocrinology 2006 4(Suppl 1):S8
    Content type: Review Published on:

    This article is part of a Supplement: Volume 4 Supplement 1

  32. Endometriosis is one of the most common causes of chronic pelvic pain and infertility in women in the reproductive age group. Although the existence of this disease has been known for over 100 years our curren...

    Authors: Julie M Hastings and Asgerally T Fazleabas
    Citation: Reproductive Biology and Endocrinology 2006 4(Suppl 1):S7
    Content type: Review Published on:

    This article is part of a Supplement: Volume 4 Supplement 1

  33. Macaques are menstruating nonhuman primates that provide important animal models for studies of hormonal regulation in the uterus. In women and macaques the decline of progesterone (P) at the end of the cycle ...

    Authors: Ov D Slayden and Robert M Brenner
    Citation: Reproductive Biology and Endocrinology 2006 4(Suppl 1):S6
    Content type: Review Published on:

    This article is part of a Supplement: Volume 4 Supplement 1

  34. This review focuses on the complex events that occur in the endometrium after progesterone is withdrawn (or blocked) and menstrual bleeding ensues. A detailed understanding of these local mechanisms will enhan...

    Authors: Hilary OD Critchley, Rodney W Kelly, David T Baird and Robert M Brenner
    Citation: Reproductive Biology and Endocrinology 2006 4(Suppl 1):S5
    Content type: Review Published on:

    This article is part of a Supplement: Volume 4 Supplement 1

  35. Endometrium is a dynamic tissue that responds on a cyclic basis to circulating levels of the ovarian-derived steroid hormones, estradiol and progesterone. Functional genomics has enabled a global approach to u...

    Authors: Linda C Giudice
    Citation: Reproductive Biology and Endocrinology 2006 4(Suppl 1):S4
    Content type: Review Published on:

    This article is part of a Supplement: Volume 4 Supplement 1

  36. This contribution will trace some of the many seminal studies on the female uterus (endometrium) over the centuries and conclude with a description of some current research initiatives in our laboratory. Numer...

    Authors: William C Okulicz
    Citation: Reproductive Biology and Endocrinology 2006 4(Suppl 1):S3
    Content type: Review Published on:

    This article is part of a Supplement: Volume 4 Supplement 1

  39. Fluid homeostasis is critical for normal function of the male reproductive tract and aquaporins (AQP) play an important role in maintenance of this water and ion balance. Several AQPs have been identified in t...

    Authors: Patrícia Picciarelli-Lima, André G Oliveira, Adelina M Reis, Evanguedes Kalapothakis, Germán AB Mahecha, Rex A Hess and Cleida A Oliveira
    Citation: Reproductive Biology and Endocrinology 2006 4:51
    Content type: Research Published on:

  40. Ovarian follicular development is primarily dependent on pituitary gonadotropins. Identification of gonadotropin-inducible genes in the ovary is one of the effective approaches for the study of follicular deve...

    Authors: Miki Yoshino, Tetsuya Mizutani, Kazuya Yamada, Takashi Yazawa, Hiroko Ogata-Kawata, Toshio Sekiguchi, Takashi Kajitani and Kaoru Miyamoto
    Citation: Reproductive Biology and Endocrinology 2006 4:50
    Content type: Research Published on:

  41. Environmental estrogenic compounds which bind to the estrogen receptor (ER) can block or alter endogenous functions of estrogen in reproductive and developmental stages. A microarray technology is a very valua...

    Authors: Eui-Ju Hong, Se-Hyung Park, Kyung-Chul Choi, Peter CK Leung and Eui-Bae Jeung
    Citation: Reproductive Biology and Endocrinology 2006 4:49
    Content type: Research Published on:

  42. Mammalian sperm-oocyte interaction at fertilization involves several combined interactions between integrins on the oocyte and integrin ligands (disintegrins) on the sperm. Recent research has indicated the ab...

    Authors: Carla Tatone and Maria Cristina Carbone
    Citation: Reproductive Biology and Endocrinology 2006 4:48
    Content type: Research Published on:

  43. Estradiol (E2) and progesterone (P) are well known regulators of progesterone receptor (PR) expression in the rat uterus. However, it is not known which receptor subtypes are involved. Little knowledge exist a...

    Authors: Lena Sahlin, Britt Masironi, Sonja Åkerberg and Håkan Eriksson
    Citation: Reproductive Biology and Endocrinology 2006 4:47
    Content type: Research Published on:

  44. In mammals it is well known that infections can lead to alterations in reproductive function. As part of the innate immune response, a number of cytokines and other immune factors is produced during bacterial ...

    Authors: Simon MacKenzie, Nuria Montserrat, Mario Mas, Laura Acerete, Lluis Tort, Aleksei Krasnov, Frederick W Goetz and Josep V Planas
    Citation: Reproductive Biology and Endocrinology 2006 4:46
    Content type: Research Published on:

  45. The uterus is exposed to changes such as enlargement and distension during pregnancy and labor. In these processes and in the process of cervical ripening, proprioceptive information is likely to be of great i...

    Authors: Berith K Tingaker, Gunvor Ekman-Ordeberg and Sture Forsgren
    Citation: Reproductive Biology and Endocrinology 2006 4:45
    Content type: Research Published on:

  47. There is evidence that one gonad has functional predominance. The present study analyzed the acute effects of unilateral ovariectomy (ULO) and blocking the cholinergic system, by injecting atropine sulfate (AT...

    Authors: María E Cruz, Angélica Flores, María T Palafox, Griselda Meléndez, Jorge O Rodríguez, Roberto Chavira and Roberto Domínguez
    Citation: Reproductive Biology and Endocrinology 2006 4:43
    Content type: Research Published on:

  48. The existing dogma that the former term ovarian "germinal epithelium" resulted from a mistaken belief that it could give rise to new germ cells is now strongly challenged.

    Authors: Takashi Nishida and Naoyo Nishida
    Citation: Reproductive Biology and Endocrinology 2006 4:42
    Content type: Debate Published on:

  49. The coexistence of endometrial and immune cells during decidualization is preserved by the ability of endometrial cells to regulate the cytotoxic immune activity and their capability to be resistant to immune-...

    Authors: Lukasz Wicherek, Magdalena Dutsch-Wicherek, Krystyna Galazka, Tomasz Banas, Tadeusz Popiela, Agata Lazar and Beata Kleinrok-Podsiadlo
    Citation: Reproductive Biology and Endocrinology 2006 4:41
    Content type: Research Published on:

  50. The Deleted-in-AZoospermia-Like (DAZL) gene has homologs required for germ cell development in many organisms. Recently, we showed that there are several common polymorphisms within the DAZL gene that are associa...

    Authors: Joyce Y Tung, Mitchell P Rosen, Lawrence M Nelson, Paul J Turek, John S Witte, Daniel W Cramer, Marcelle I Cedars and Renee A Reijo-Pera
    Citation: Reproductive Biology and Endocrinology 2006 4:40
    Content type: Research Published on:
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