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  1. Aromatase inhibitors effectively delay epiphysial maturation in boys and improve testosterone levels in adult men Therefore, aromatase inhibitors may be used to increase adult height in boys with gonadotropin-...

    Authors: Willem de Ronde and Frank H de Jong
    Citation: Reproductive Biology and Endocrinology 2011 9:93
    Content type: Review Published on:

  2. Aromatase, the key enzyme in estrogen biosynthesis, converts androstenedione to estrone and testosterone to estradiol. The enzyme is expressed in various tissues such as ovary, placenta, bone, brain, skin, and...

    Authors: Shabana I Khan, Jianping Zhao, Ikhlas A Khan, Larry A Walker and Asok K Dasmahapatra
    Citation: Reproductive Biology and Endocrinology 2011 9:91
    Content type: Review Published on:

  3. This systematic review aims to assess the efficacy of aromatase inhibitors (AIs) in treating pain symptoms caused by endometriosis. A comprehensive literature search was conducted to identify all the published...

    Authors: Simone Ferrero, David J Gillott, Pier L Venturini and Valentino Remorgida
    Citation: Reproductive Biology and Endocrinology 2011 9:89
    Content type: Review Published on:

  5. Aromatase inhibitors have been introduced as a new treatment modality that could challenge clomiphene citrate as an ovulation induction regiment in patients with PCOS. Although several randomized trials have b...

    Authors: Evangelos G Papanikolaou, Nikolaos P Polyzos, Peter Humaidan, George Pados, Ernesto Bosch, Herman Tournaye and Basil Tarlatzis
    Citation: Reproductive Biology and Endocrinology 2011 9:85
    Content type: Review Published on:

  6. The objective of this study was to compare letrozole-stimulated cycles to natural cycles in 208 patients undergoing intrauterine insemination (IUI) between July of 2004 and January of 2007. Group I (n = 47) re...

    Authors: Mohamed A Bedaiwy, Mahmoud A Abdelaleem, Mostafa Hussein, Noha Mousa, Lisa N Brunengraber and Robert F Casper
    Citation: Reproductive Biology and Endocrinology 2011 9:83
    Content type: Research Published on:

  7. In the last two decades, pregnancy rates for patients undergoing in-vitro fertilisation (IVF) have significantly increased. Some of the major advances responsible for this improvement were the introduction of ...

    Authors: Ernesto Bosch and Diego Ezcurra
    Citation: Reproductive Biology and Endocrinology 2011 9:82
    Content type: Debate Published on:

  8. We performed this retrospective case-control study analyzing 428 first-attempt in vitro fertilization (IVF) cycles, among which 254 involved women with a previous or present diagnosis of ovarian endometriosis....

    Authors: Francesca Bongioanni, Alberto Revelli, Gianluca Gennarelli, Daniela Guidetti, Luisa Delle Delle Piane and Jan Holte
    Citation: Reproductive Biology and Endocrinology 2011 9:81
    Content type: Research Published on:

  9. Serum anti-Müllerian hormone (AMH) had been proposed as a marker of ovarian reserve. The aim of this study was to evaluate the impact of endometrioma and laparoscopic cystectomy on ovarian reserve as measured ...

    Authors: Yuh-Ming Hwu, Frank Shao-Ying Wu, Sheng-Hsiang Li, Fang-Ju Sun, Ming-Huei Lin and Robert Kuo-Kuang Lee
    Citation: Reproductive Biology and Endocrinology 2011 9:80
    Content type: Research Published on:

  10. After ovulation in the cow, the corpus luteum (CL) rapidly develops within a few days with angiogenesis and progesterone production. CL formation resembles an inflammatory response due to the influx of immune ...

    Authors: Sineenard Jiemtaweeboon, Koumei Shirasuna, Akane Nitta, Ayumi Kobayashi, Hans-Joachim Schuberth, Takashi Shimizu and Akio Miyamoto
    Citation: Reproductive Biology and Endocrinology 2011 9:79
    Content type: Research Published on:

  11. The objective of the present study is to assess viability tests and to evaluate follicle ovarian tissue quality after freezing-thawing procedures.

    Authors: Ghaya Merdassi, Claire Mazoyer, Jean F Guerin, Ali Saad, Bruno Salle and Jacqueline Lornage
    Citation: Reproductive Biology and Endocrinology 2011 9:78
    Content type: Methodology Published on:

  12. Angiogenic factors are involved in formation of new blood vessels required for placental development and function; and critical for fetal growth and development. Soluble fms-like tyrosine kinase 1(sFlt-1) is a...

    Authors: Marni Jacobs, Natasha Nassar, Christine L Roberts, Ruth Hadfield, Jonathan M Morris and Anthony W Ashton
    Citation: Reproductive Biology and Endocrinology 2011 9:77
    Content type: Review Published on:

  13. Polycystic ovary syndrome (PCOS) is a complex disease having both genetic and environmental components. Candidate genes with insulin metabolism have been hypothesized to be involved in the etiology of this syn...

    Authors: Xinghua Xu, Han Zhao, Yuhua Shi, Li You, Yuehong Bian, Yueran Zhao and Zi-Jiang Chen
    Citation: Reproductive Biology and Endocrinology 2011 9:76
    Content type: Research Published on:

  15. The purpose of the study was to determine if the effect of llama OIF on LH secretion is mediated by stimulation of the hypothalamus or pituitary gland.

    Authors: Mauricio E Silva, Juan P Smulders, Monserrat Guerra, Ximena P Valderrama, Claudia Letelier, Gregg P Adams and Marcelo H Ratto
    Citation: Reproductive Biology and Endocrinology 2011 9:74
    Content type: Research Published on:

  16. During the peri-implantation period, the embryo adheres to an adequately prepared or receptive endometrial surface epithelium. Abnormal embryo adhesion to the endometrium results in embryo implantation failure...

    Authors: Joanne Yap, Caroline FH Foo, Ming Yee Lee, Peter G Stanton and Evdokia Dimitriadis
    Citation: Reproductive Biology and Endocrinology 2011 9:73
    Content type: Research Published on:

  17. SERPINs (serine protease inhibitors) regulate proteases involving fibrinolysis, coagulation, inflammation, cell mobility, cellular differentiation and apoptosis. This study aimed to investigate differentially ...

    Authors: Ken-Go Hayashi, Koichi Ushizawa, Misa Hosoe and Toru Takahashi
    Citation: Reproductive Biology and Endocrinology 2011 9:72
    Content type: Research Published on:

  18. To elucidate the molecular mechanisms underling hydration during oocyte maturation, we characterized the structure of Japanese eel (Anguilla japonica) novel-water selective aquaporin 1 (AQP1b) that thought to be ...

    Authors: Hirohiko Kagawa, Takafumi Kishi, Koichiro Gen, Yukinori Kazeto, Ryota Tosaka, Hajime Matsubara, Takahiro Matsubara and Sayumi Sawaguchi
    Citation: Reproductive Biology and Endocrinology 2011 9:71
    Content type: Research Published on:

  19. Diabetes mellitus is a chronic disease that can result in various medical, psychological and sexual dysfunctions (SD) if not properly managed. SD in men is a common under-appreciated complication of diabetes. ...

    Authors: William KBA Owiredu, Nafiu Amidu, Huseini Alidu, Charity Sarpong and Christian K Gyasi-Sarpong
    Citation: Reproductive Biology and Endocrinology 2011 9:70
    Content type: Research Published on:

  20. Mating changes the mechanism by which E2 regulates oviductal egg transport, from a non-genomic to a genomic mode. Previously, we found that E2 increased the expression of several genes in the oviduct of mated ...

    Authors: Mariana Ríos, Alexis Parada-Bustamante, Luis A Velásquez, Horacio B Croxatto and Pedro A Orihuela
    Citation: Reproductive Biology and Endocrinology 2011 9:69
    Content type: Research Published on:

  21. In the majority of vertebrates, gametogenesis and gamete-release depend on the pulsatile secretion of luteinizing hormone-releasing hormone (LHRH) from the hypothalamus. Studies attempting to artificially stim...

    Authors: Aimee J Silla
    Citation: Reproductive Biology and Endocrinology 2011 9:68
    Content type: Research Published on:

  23. Cystic ovarian disease (COD) is an important cause of abnormal estrous behavior and infertility in dairy cows. COD is mainly observed in high-yielding dairy cows during the first months post-partum, a period o...

    Authors: Alfonso H Paredes, Natalia R Salvetti, Ariel E Diaz, Bibiana E Dallard, Hugo H Ortega and Hernan E Lara
    Citation: Reproductive Biology and Endocrinology 2011 9:66
    Content type: Research Published on:

  24. We describe the development of an electrochemical sensor array for monitoring the proliferation effects of cissus populnea plant extracts on TM4 Sertoli cells.

    Authors: Elizabeth Osibote, Naumih Noah, Omowunmi Sadik, Dennis McGee and Modupe Ogunlesi
    Citation: Reproductive Biology and Endocrinology 2011 9:65
    Content type: Methodology Published on:

  25. Placental hCG and pitutary LH transduce signals in target tissues through a common receptor (LHCGR). We demonstrate that recombinant LHCGR proteins which include the hormone-binding domain are secreted from tr...

    Authors: Anne E Chambers, Paul F Stanley, Harpal Randeva and Subhasis Banerjee
    Citation: Reproductive Biology and Endocrinology 2011 9:64
    Content type: Research Published on:

  26. PreImplantation Factor (PIF), a novel peptide secreted by viable embryos is essential for pregnancy: PIF modulates local immunity, promotes decidual pro-adhesion molecules and enhances trophoblast invasion. To...

    Authors: Christopher W Stamatkin, Roumen G Roussev, Mike Stout, Victor Absalon-Medina, Sivakumar Ramu, Chelsi Goodman, Carolyn B Coulam, Robert O Gilbert, Robert A Godke and Eytan R Barnea
    Citation: Reproductive Biology and Endocrinology 2011 9:63
    Content type: Research Published on:

  27. Although chicken oviduct is a useful model and target tissue for reproductive biology and transgenesis, little is known because of the highly specific hormonal regulation and the lack of fundamental researches...

    Authors: Jin Gyoung Jung, Whasun Lim, Tae Sub Park, Jin Nam Kim, Beom Ku Han, Gwonhwa Song and Jae Yong Han
    Citation: Reproductive Biology and Endocrinology 2011 9:62
    Content type: Research Published on:

  28. Menarche delay has been reported in adolescent females with type 1 diabetes (T1DM), perhaps due to poor glycemic control. We sought to compare age at menarche between adolescent females with T1DM and national ...

    Authors: Bahareh M Schweiger, Janet K Snell-Bergeon, Rossana Roman, Kim McFann and Georgeanna J Klingensmith
    Citation: Reproductive Biology and Endocrinology 2011 9:61
    Content type: Review Published on:

  29. Single blastocyst transfer has the advantage of maximizing the fresh single pregnancy rate. However, in patients with a low number of good quality embryos on day 3, it remains unclear whether immediate embryo ...

    Authors: Dominic Stoop, Lisbet Van Landuyt, Etienne Van den Abbeel, Michel Camus, Greta Verheyen and Paul Devroey
    Citation: Reproductive Biology and Endocrinology 2011 9:60
    Content type: Research Published on:

  30. It has been suggested that inhibin secretion is altered in women with the polycystic ovary syndrome (PCOS). However, the contribution of a preceding luteal phase has not been taken into account. The aim of the...

    Authors: Konstantinos Dafopoulos, Christos Venetis, Christina I Messini, Spyros Pournaras, George Anifandis, Antonios Garas and Ioannis E Messinis
    Citation: Reproductive Biology and Endocrinology 2011 9:59
    Content type: Research Published on:

  31. We compared two methods of zona pellucida drilling. 213 embryos were biopsied with acid Tyrode. Each biopsy took 3 minutes and the entire procedure ~29 minutes. 5% of blastomeres lysed, 49% of embryos became b...

    Authors: Selmo Geber, Renata Bossi, Cintia B Lisboa, Marcelo Valle and Marcos Sampaio
    Citation: Reproductive Biology and Endocrinology 2011 9:58
    Content type: Methodology Published on:

  32. The second to fourth digit ratio (2D:4D) is used as a marker of prenatal sex hormone exposure. The objective of this study was to examine whether circulating concentrations of sex hormones and SHBG measured in...

    Authors: David C Muller, Graham G Giles, Julie Bassett, Howard A Morris, John T Manning, John L Hopper, Dallas R English and Gianluca Severi
    Citation: Reproductive Biology and Endocrinology 2011 9:57
    Content type: Research Published on:

  33. PMP22, a member of the GAS3 family of tetraspan proteins, is associated with a variety of neurological diseases. Previous studies have shown that PMP22 is expressed in proliferative endometrium, but its functi...

    Authors: Rajiv G Rao, Deepthi Sudhakar, Claire P Hogue, Stephanie Amici, Lynn K Gordon, Jonathan Braun, Lucia Notterpek, Lee Goodglick and Madhuri Wadehra
    Citation: Reproductive Biology and Endocrinology 2011 9:56
    Content type: Research Published on:

  34. Sigmodontinae, known as "New World rats and mice," is a large subfamily of Cricetidae for which we herein provide the first comprehensive investigation of the placenta.

    Authors: Phelipe O Favaron, Anthony M Carter, Carlos E Ambrósio, Adriana C Morini, Andrea M Mess, Moacir F de Oliveira and Maria A Miglino
    Citation: Reproductive Biology and Endocrinology 2011 9:55
    Content type: Research Published on:

  35. Ovarian sex hormones (OSHs) are implicated in cardiovascular function. It has been shown that OSHs play an important role in the long term regulation of cardiac sarcoplasmic reticulum (SR) function and contrac...

    Authors: Altemar S Paigel, Rogerio F Ribeiro Junior, Aurelia A Fernandes, Gabriel P Targueta, Dalton V Vassallo and Ivanita Stefanon
    Citation: Reproductive Biology and Endocrinology 2011 9:54
    Content type: Research Published on:

  36. This study evaluated whether there is a relationship between the zona pellucida birefringence (ZP-BF) intensity and the nuclear (NM) and cytoplasmic (CM) in vitro maturation of human oocytes from stimulated cy...

    Authors: Claudia G Petersen, Laura D Vagnini, Ana L Mauri, Fabiana C Massaro, Liliane FI Silva, Mario Cavagna, Ricardo LR Baruffi, Joao BA Oliveira and José G Franco Jr
    Citation: Reproductive Biology and Endocrinology 2011 9:53
    Content type: Research Published on:

  37. Throughout oogenesis, cell-cell communication via gap junctions (GJs) between oocytes and surrounding follicle cells (theca and granulosa cells), and/or amongst follicle cells is required for successful follic...

    Authors: Yoji Yamamoto, J Adam Luckenbach, Mollie A Middleton and Penny Swanson
    Citation: Reproductive Biology and Endocrinology 2011 9:52
    Content type: Research Published on:

  38. Vascular endothelial growth factor receptor-2 (VEGFR2) plays a pivotal role in angiogenesis by eliciting vascular endothelial cell growth when bound to VEGF, a powerful pro-angiogenic ligand. While Vegf and Ve...

    Authors: Jonathan M Greene, Chad W Dunaway, Susan D Bowers, Brian J Rude, Jean M Feugang and Peter L Ryan
    Citation: Reproductive Biology and Endocrinology 2011 9:51
    Content type: Methodology Published on:

  39. NASP (Nuclear Autoantigenic Sperm Protein) is a histone chaperone that is present in all dividing cells. NASP has two splice variants: tNASP and sNASP. Only cancer, germ, transformed, and embryonic cells have ...

    Authors: Oleg M Alekseev, Richard T Richardson, James K Tsuruta and Michael G O'Rand
    Citation: Reproductive Biology and Endocrinology 2011 9:50
    Content type: Research Published on:

  40. Research on antimicrobial cationic peptides (AMPs) has gained pace toward using their potential to replace conventional antibiotics. These peptides preferentially interact with negatively charged membrane lipi...

    Authors: Jayasree Sengupta, Meraj Alam Khan, Berthold Huppertz and Debabrata Ghosh
    Citation: Reproductive Biology and Endocrinology 2011 9:49
    Content type: Research Published on:

  41. Pregnancy-associated plasma protein A2 (PAPPA2) is an insulin-like growth factor-binding protein (IGFBP) protease expressed at high levels in the placenta and upregulated in pregnancies complicated by preeclam...

    Authors: Pamela K Wagner, Aki Otomo and Julian K Christians
    Citation: Reproductive Biology and Endocrinology 2011 9:48
    Content type: Research Published on:

  42. There is clinical evidence to show that sperm DNA damage could be a marker of sperm quality and extensive data exist on the relationship between DNA damage and male fertility status. Detecting such damage in s...

    Authors: Nassira Zribi, Nozha Feki Chakroun, Henda Elleuch, Fatma Ben Abdallah, Afifa Sellami Ben Hamida, Jalel Gargouri, Faiza Fakhfakh and Leila Ammar Keskes
    Citation: Reproductive Biology and Endocrinology 2011 9:47
    Content type: Research Published on:

  43. Tribbles 3 (TRB3) affects insulin signalling by inhibiting insulin-stimulated Akt phosphorylation and subsequent activation. A single nucleotide polymorphism located in the second extron of the human TRB3 gene...

    Authors: Xue Zhang, Li Fu, Qiufang Zhang, Liying Yan, Yanmin Ma, Binbin Tu, Nana Liu and Jie Qiao
    Citation: Reproductive Biology and Endocrinology 2011 9:46
    Content type: Research Published on:

  44. Large volumes of lymph can be collected from the eye-sacs of bubble-eye goldfish. We attempted to induce vitellogenin (Vtg) in the eye-sac lymph of bubble-eye goldfish and develop a method for visualizing Vtg ...

    Authors: Yohei Matsuda, Yoshie Ito, Hisashi Hashimoto, Hayato Yokoi and Tohru Suzuki
    Citation: Reproductive Biology and Endocrinology 2011 9:45
    Content type: Methodology Published on:

  45. Authors: Amelie Fassbender, Peter Simsa, Cleophas M Kyama, Etienne Waelkens, Attila Mihalyi, Christel Meuleman, Olivier Gevaert, Raf Van de Plas, Bart de Moor and Thomas M D'Hooghe
    Citation: Reproductive Biology and Endocrinology 2011 9:44
    Content type: Erratum Published on:

    The original article was published in Reproductive Biology and Endocrinology 2010 8:123

  46. Proprotein convertase 5/6 (PC5/6) is critical for embryo implantation in women, regulating both uterine epithelial receptivity and stromal cell decidualization. PC5/6 is likewise essential for implantation in ...

    Authors: Peter K Nicholls, Zhaogui Sun, Sophea Heng, Ying Li, Jian Wang and Guiying Nie
    Citation: Reproductive Biology and Endocrinology 2011 9:43
    Content type: Research Published on:

  48. In the present study we analyzed the existence of asymmetry in the secretion of steroid hormones in pre-pubertal female rats treated with unilateral ovariectomy (ULO) or unilateral perforation of the abdominal...

    Authors: Leticia Morales-Ledesma, Deyra A Ramírez, Elizabeth Vieyra, Angélica Trujillo, Roberto Chavira, Mario Cárdenas and Roberto Domínguez
    Citation: Reproductive Biology and Endocrinology 2011 9:41
    Content type: Methodology Published on:

  49. Nucleoplasmin 2 (NPM2) is an oocyte-specific nuclear protein essential for nuclear and nucleolar organization and early embryonic development. The aims of this study were to clone the bovine NPM2 gene, determine ...

    Authors: Brandon M Lingenfelter, Swamy K Tripurani, Jyothsna Tejomurtula, George W Smith and Jianbo Yao
    Citation: Reproductive Biology and Endocrinology 2011 9:40
    Content type: Research Published on:

  50. Despite the heavy burden and impact of the polycystic ovary syndrome (PCOS) in reproduction and public health, estimates regarding its prevalence at community levels are limited. We aimed to ascertain prevalen...

    Authors: Fahimeh Ramezani Tehrani, Masoumeh Simbar, Maryam Tohidi, Farhad Hosseinpanah and Fereidoun Azizi
    Citation: Reproductive Biology and Endocrinology 2011 9:39
    Content type: Research Published on:
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Reproductive Biology and Endocrinology

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