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Fig. 8 | Reproductive Biology and Endocrinology

Fig. 8

From: Artificial ovaries constructed from biodegradable chitin-based hydrogels with the ability to restore ovarian endocrine function and alleviate osteoporosis in ovariectomized mice

Fig. 8

Artificial ovaries transplantation restored ovariectomised (OVX)-induced bone loss after transplantation. (a) Representative images of haematoxylin and eosin (H&E) staining and (b) micro-computed tomography (micro-CT) imaging analysis at 6 weeks after transplantation. (c) Representative images of H&E staining and (d) micro-CT imaging analysis at 10 weeks after transplantation. (e) Quantitative analyses of BV/TV%, Tb.Sp, Tb.N, Tb.Th, BMD, and SMI. The data are represented as the mean ± standard deviation. * indicates significance at P < 0.05 compared with the sham groups; # indicates significance at P < 0.05 compared with the OVX groups; $ indicates significance at P < 0.05 compared with the CTP-F groups; & indicates significance at P < 0.05 compared with ALG groups, determined using one-way ANOVA, followed by Student–Newman–Keuls post-hoc analysis

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