Fig. 2From: Artificial ovaries constructed from biodegradable chitin-based hydrogels with the ability to restore ovarian endocrine function and alleviate osteoporosis in ovariectomized miceGrowth and hormone secretion. (a) Morphology of follicles cultured from days 0–12. (b) Growth curve over a 12-day culture period. (c) Follicular survival rate in vitro measured on days 6 and 12. (d-f) Androstenedione, oestradiol, and progesterone levels secreted into the culture medium on days 6 and 12. The data are represented as the mean ± standard deviation. * indicates significance at P < 0.05 compared with 2D, and # indicates significance at P < 0.05 compared with alginate hydrogels (ALG) determined using one-way ANOVA, followed by Student–Newman–Keuls post-hoc analysisBack to article page